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不仅仅是体重问题:一例严重肥胖患者的体外膜肺氧合治疗病例报告

Not just a matter of weight: A case report of ECMO treatment in a severely obese patient.

作者信息

Schiavoni L, Mattei A, Pascarella G, Piliego C, Biondo G, Strumia A, Agrò Felice E

机构信息

Unit of Anesthesia, Intensive Care and Pain Management, Department of Medicine, Università Campus Bio-Medico di Roma, via Álvaro del Portillo 21, 00128 Rome, Italy.

Unit of Anesthesia, Intensive Care and Pain Management, Department of Medicine, Ospedale di Velletri, Via Orti Ginnetti n.7, 00049 Velletri, RM, Italy.

出版信息

Obes Res Clin Pract. 2022 Jul-Aug;16(4):346-348. doi: 10.1016/j.orcp.2022.07.008. Epub 2022 Jul 28.

DOI:10.1016/j.orcp.2022.07.008
PMID:35909046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9445800/
Abstract

The ELSO Guidelines list a BMI ≥ 40 kg/m among the relative contraindications to give ECMO treatment in SARS - COV2 patients. We describe a case of a 52-year-old with BMI 50.21 kg/m, admitted to the intensive care unit (ICU) with severe respiratory conditions and successfully treated with extracorporeal membrane oxygenation (ECMO). The application of veno-venous (VV) ECMO will evolve as far as we understand the pathophysiology of the COVID-19 disease and will probably have a determinant role in management of patient with refractory hypoxemia, whose ventilation management is difficult, even in case of severe obesity.

摘要

体外生命支持组织(ELSO)指南将BMI≥40kg/m²列为2019冠状病毒病(SARS-CoV2)患者接受体外膜肺氧合(ECMO)治疗的相对禁忌证。我们报告一例52岁、BMI为50.21kg/m²的患者,因严重呼吸疾病入住重症监护病房(ICU),并成功接受了体外膜肺氧合(ECMO)治疗。就我们对2019冠状病毒病病理生理学的理解而言,静脉-静脉(VV)ECMO的应用将会不断发展,并且在难治性低氧血症患者的管理中可能具有决定性作用,即使是在严重肥胖的情况下,这类患者的通气管理也很困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f75c/9445800/89bd0a2af4fa/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f75c/9445800/89bd0a2af4fa/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f75c/9445800/89bd0a2af4fa/gr1_lrg.jpg

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本文引用的文献

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Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry.COVID-19 患者的体外膜肺氧合支持:体外生命支持组织登记处的国际队列研究。
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Obesity and diabetes as high-risk factors for severe coronavirus disease 2019 (Covid-19).肥胖症和糖尿病是导致 2019 年冠状病毒病(COVID-19)重症的高危因素。
Diabetes Metab Res Rev. 2021 Feb;37(2):e3377. doi: 10.1002/dmrr.3377. Epub 2020 Jul 20.
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ECMO use in COVID-19: lessons from past respiratory virus outbreaks-a narrative review.ECMO 在 COVID-19 中的应用:来自过去呼吸道病毒暴发的经验教训——一篇叙述性综述。
Crit Care. 2020 Jun 6;24(1):301. doi: 10.1186/s13054-020-02979-3.
7
COVID-19 diagnosis and management: a comprehensive review.COVID-19 的诊断与管理:全面综述。
J Intern Med. 2020 Aug;288(2):192-206. doi: 10.1111/joim.13091. Epub 2020 May 13.
8
Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation.为新冠肺炎重症患者做准备:体外膜肺氧合的潜在作用
JAMA. 2020 Apr 7;323(13):1245-1246. doi: 10.1001/jama.2020.2342.
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