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用于手术伤口闭合的组织粘合剂固化时间的优化。

Optimization of tissue adhesive curing time for surgical wound closure.

作者信息

Wellington Ian J, Hawthorne Benjamin C, Dorsey Caitlin, Connors John P, Mazzocca Augustus D, Solovyova Olga

机构信息

Department of Orthopedics, University of Connecticut, Farmington, Connecticut, USA.

Department of Orthopedics, Massachussetts General Hospital, Boston, Massachusetts, USA.

出版信息

Bone Jt Open. 2022 Aug;3(8):607-610. doi: 10.1302/2633-1462.38.BJO-2022-0050.R1.

DOI:10.1302/2633-1462.38.BJO-2022-0050.R1
PMID:35909340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9422901/
Abstract

AIMS

Tissue adhesives (TAs) are a commonly used adjunct to traditional surgical wound closures. However, TAs must be allowed to dry before application of a surgical dressing, increasing operating time and reducing intraoperative efficiency. The goal of this study is to identify a practical method for decreasing the curing time for TAs.

METHODS

Six techniques were tested to determine which one resulted in the quickest drying time for 2-octyle cyanoacrylate (Dermabond) skin adhesive. These were nothing (control), fanning with a hand (Fanning), covering with a hand (Covering), bringing operating room lights close (OR Lights), ultraviolet lights (UV Light), or prewarming the TA applicator in a hot water bath (Hot Water Bath). Equal amounts of TA were applied to a reproducible plexiglass surface and allowed to dry while undergoing one of the six techniques. The time to complete dryness was recorded for ten specimens for each of the six techniques.

RESULTS

Use of the Covering, OR Lights, and Hot Water Bath techniques were associated with a 25- (p = 0.042), 27- (p = 0.023), and 30-second (p = 0.009) reduction in drying time, respectively, when compared to controls. The UV Light (p = 0.404) and Fanning (p = 1.000) methods had no effect on drying time.

CONCLUSION

Use of the Covering, OR Lights, and Hot Water Bath techniques present a means for reducing overall operating time for surgeons using TA for closure augmentation, which can increase intraoperative efficiency. Further studies are needed to validate this in vivo.Cite this article:  2022;3(8):607-610.

摘要

目的

组织粘合剂(TAs)是传统手术伤口缝合常用的辅助材料。然而,在应用手术敷料之前,必须让TAs干燥,这增加了手术时间并降低了术中效率。本研究的目的是确定一种减少TAs固化时间的实用方法。

方法

测试了六种技术,以确定哪种技术能使2-辛基氰基丙烯酸酯(皮肤粘合剂)干燥时间最短。这六种技术分别是不做处理(对照)、用手扇风(扇风)、用手覆盖(覆盖)、将手术室灯光靠近(手术室灯光)、紫外线灯(紫外线灯)或在热水浴中预热TA涂抹器(热水浴)。将等量的TA涂抹在可重复使用的有机玻璃表面,并在采用六种技术之一的情况下使其干燥。记录六种技术中每种技术的十个样本完全干燥所需的时间。

结果

与对照组相比,使用覆盖、手术室灯光和热水浴技术分别使干燥时间缩短了25秒(p = 0.042)、27秒(p = 0.023)和30秒(p = 0.009)。紫外线灯(p = 0.404)和扇风(p = 1.000)方法对干燥时间没有影响。

结论

使用覆盖、手术室灯光和热水浴技术为使用TA进行闭合增强的外科医生提供了一种减少总体手术时间的方法,这可以提高术中效率。需要进一步的研究在体内验证这一点。引用本文:2022;3(8):607 - 610。

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