Nurmukhambetov A N, Iksymbaeva Zh S, Kruglikov R I, Meerson F Z
Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Mar-Apr;37(2):345-9.
Injections to rats of antibiotic adriblastin activating lipids peroxide oxidation directly after elaboration of defensive conditioned reflexes, elicit retrograde amnesia. Administration of antioxidant ional before the administration of adriblastin prevents this effect. It is suggested that activation of lipids peroxide oxidation disturbs the process of consolidation.
在大鼠建立防御性条件反射后立即注射抗生素阿霉素,可直接激活脂质过氧化反应,引发逆行性遗忘。在注射阿霉素之前给予抗氧化剂离子可防止这种效应。提示脂质过氧化反应的激活会干扰巩固过程。