Mei Yanqiu, Lin Xiaofeng, He Chen, Zeng Weijia, Luo Yan, Liu Chenghao, Liu Zhehao, Yang Min, Kuang Ying, Huang Qitong
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province, Key Laboratory of Biomedical Sensors of Ganzhou, School of Public Health and Health Management, School of Medical and Information Engineering, Gannan Medical University, Ganzhou, China.
Oil-Tea in Medical Health Care and Functional Product Development Engineering Research Center in Jiangxi, The Science Research Center, School of Pharmacy, Gannan Medical University, Ganzhou, China.
Front Bioeng Biotechnol. 2022 Jul 15;10:952510. doi: 10.3389/fbioe.2022.952510. eCollection 2022.
Coronavirus disease 19 (COVID-19) is still a major public health concern in many nations today. COVID-19 transmission is now controlled mostly through early discovery, isolation, and therapy. Because of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the contributing factor to COVID-19, establishing timely, sensitive, accurate, simple, and budget detection technologies for the SARS-CoV-2 is urgent for epidemic prevention. Recently, several electrochemical DNA biosensors have been developed for the rapid monitoring and detection of SARS-CoV-2. This mini-review examines the latest improvements in the detection of SARS-COV-2 utilizing electrochemical DNA biosensors. Meanwhile, this mini-review summarizes the problems faced by the existing assays and puts an outlook on future trends in the development of new assays for SARS-CoV-2, to provide researchers with a borrowing role in the generation of different assays.
新型冠状病毒肺炎(COVID-19)如今仍是许多国家主要的公共卫生问题。目前,COVID-19的传播主要通过早期发现、隔离和治疗来控制。由于严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是导致COVID-19的因素,因此建立及时、灵敏、准确、简便且经济的SARS-CoV-2检测技术对于疫情防控至关重要。最近,已经开发了几种用于快速监测和检测SARS-CoV-2的电化学DNA生物传感器。本综述探讨了利用电化学DNA生物传感器检测SARS-CoV-2的最新进展。同时,本综述总结了现有检测方法面临的问题,并展望了SARS-CoV-2新检测方法的未来发展趋势,为研究人员在开发不同检测方法时提供借鉴作用。