Calovi Massimo, Meschini Stefania, Condello Maria, Rossi Stefano
Department of Industrial Engineering, University of Trento, Trento 38123, Italy.
National Center for Drug Research and Evaluation, National Institute of Health, Rome 00161, Italy.
ACS Omega. 2022 Jul 15;7(29):25650-25662. doi: 10.1021/acsomega.2c02872. eCollection 2022 Jul 26.
Today, the use of silver in surfaces for public environments is very frequent, as it ensures high antimicrobial activities, avoiding the continuous disinfection of the surfaces themselves. Similarly, thanks to its interesting combination of technological properties, anodized aluminum is widely employed in the production of components for applications in public spaces. Therefore, this work describes a simple method of the codeposition of silver and anodized aluminum to combine the remarkable properties of AlO layers with the antibacterial performances of silver. The effect of silver in modifying the durability features of the anodized aluminum layer was evaluated by means of various accelerated degradation techniques, such as the exposure in a climatic chamber to UV-B radiation or an aggressive atmosphere simulated by the Kesternich test. These analyses showed the good compatibility between Ag and the alumina matrix, whose durability performances were not particularly influenced by silver. Furthermore, the composite layers did not express relevant cytotoxicity activity, as evidenced by Trypan blue flow cytometry analysis and microscopy observations, ensuring the possible use of this material in applications in close contact with humans. This same conclusion was reached by observing an almost negligible ionic release of Ag by the composite layers, even following severe degradation of the alumina matrix due to exposure to a particular acid solution. In conclusion, this work presents an innovative material that can be used in public spaces, thanks to its interesting combination of high durability and low cytotoxicity.
如今，银在公共环境表面的应用非常频繁，因为它能确保高抗菌活性，避免对表面本身进行持续消毒。同样，由于其有趣的技术性能组合，阳极氧化铝被广泛用于生产公共空间应用的部件。因此，这项工作描述了一种银与阳极氧化铝共沉积的简单方法，以将AlO层的卓越性能与银的抗菌性能相结合。通过各种加速降解技术，如在气候箱中暴露于UV - B辐射或通过凯斯滕尼希试验模拟的侵蚀性气氛，评估了银对阳极氧化铝层耐久性特征的影响。这些分析表明Ag与氧化铝基体之间具有良好的相容性，其耐久性性能并未受到银的特别影响。此外，锥虫蓝流式细胞术分析和显微镜观察表明，复合层没有表现出相关的细胞毒性活性，确保了这种材料在与人类密切接触的应用中的可能用途。通过观察复合层几乎可以忽略不计的银离子释放，即使在由于暴露于特定酸性溶液而导致氧化铝基体严重降解之后，也得出了相同的结论。总之，这项工作展示了一种创新材料，由于其高耐久性和低细胞毒性的有趣组合，可用于公共空间。
