Ramrattan Amit, Mohammed Saeeda, Rahman Muhammad
Internal Medicine, Port-of-Spain General Hospital, Port of Spain, TTO.
Gastroenterology, Port-of-Spain General Hospital, Port of Spain, TTO.
Cureus. 2022 Jul 23;14(7):e27178. doi: 10.7759/cureus.27178. eCollection 2022 Jul.
Refeeding syndrome refers to a clinical condition whereby biochemical abnormalities such as hypokalemia, hypomagnesemia, and mainly hypophosphatemia occur upon recommencement of feeding, typically in malnourished catabolic patients. A 36-year-old female presented at 30 weeks gestation with hyperemesis gravidarum. During this admission, the patient developed transaminitis with low platelets prompting suspicion of hemolysis, elevated liver enzymes low platelets (HELLP) syndrome, but the concurrent findings of severe hypophosphatemia and rhabdomyolysis were not in favor of HELLP syndrome but that of refeeding syndrome. These clinical entities proved to be a diagnostic dilemma but, ultimately, the patient was managed under refeeding syndrome. The multidisciplinary approach amongst gastroenterology, internal medicine, obstetrics, hematology, and dietetics departments led to the slowing up of the titration of caloric feeds, which ultimately led to full recovery.
再喂养综合征是指一种临床状况,即在重新开始进食时,通常在营养不良的分解代谢患者中出现低钾血症、低镁血症,主要是低磷血症等生化异常。一名36岁女性在妊娠30周时因妊娠剧吐就诊。此次入院期间,患者出现转氨酶升高和血小板减少,怀疑为溶血、肝酶升高血小板减少(HELLP)综合征,但同时出现的严重低磷血症和横纹肌溶解症不支持HELLP综合征,而支持再喂养综合征。这些临床情况构成了诊断难题,但最终患者按照再喂养综合征进行治疗。胃肠病学、内科、产科、血液学和营养学部门之间的多学科方法导致热量喂养滴定速度放缓,最终实现了完全康复。