Katragadda Silpita, Miatech Jennifer L, Zboril Ashley, Echefu Gift, Negulescu Catalina
Internal Medicine Residency Program, Baton Rouge General Medical Center, Baton Rouge, USA.
Internal Medicine Residency Program, Baton Rouge Medical Center, Baton Rouge, USA.
Cureus. 2022 Jun 29;14(6):e26420. doi: 10.7759/cureus.26420. eCollection 2022 Jun.
Gonococcal endocarditis (GE) is a rare complication of disseminated gonococcal infection with significant morbidity and increasing mortality despite early diagnosis and surgical intervention. The discovery and use of antibiotics in the treatment of gonococcal infections has made this once relatively common entity a rarity. Notably, over the recent years, GE has shown an alarming resurgence for unclear reasons. The upward trend in the incidence of gonococcal infections coupled with observed antibiotic resistance may in part explain the rise in cases. GE mostly affects sexually active young people without a history of valvular heart disease. Prompt diagnosis and surgical intervention are important in the bid to mitigate poor outcomes. Management is therefore multidisciplinary; primary care clinicians who usually are the first to see this patient population should be able to make an early diagnosis and facilitate early referral for surgical intervention as indicated. Despite appropriate and timely therapy, devastating consequences of this condition are not uncommon.
淋菌性心内膜炎(GE)是播散性淋球菌感染的一种罕见并发症,尽管早期诊断并进行了手术干预,但其发病率仍很高且死亡率不断上升。抗生素在淋球菌感染治疗中的发现和应用,使这种曾经相对常见的疾病变得罕见。值得注意的是,近年来,原因不明的情况下,GE惊人地再次出现。淋球菌感染发病率的上升趋势以及观察到的抗生素耐药性可能部分解释了病例的增加。GE主要影响没有瓣膜性心脏病史的性活跃年轻人。及时诊断和手术干预对于减轻不良后果很重要。因此,管理是多学科的;通常最先接诊这类患者的初级保健临床医生应能够做出早期诊断,并根据需要促进早期转诊进行手术干预。尽管进行了适当及时的治疗,但这种疾病的毁灭性后果并不罕见。