Jonason David E, Linden Michael, Trikudanathan Guru
Internal Medicine, University of Minnesota Medical Center, Minneapolis, USA.
Laboratory Medicine and Pathology, University of Minnesota Medical Center, Minneapolis, USA.
Cureus. 2022 Jun 29;14(6):e26424. doi: 10.7759/cureus.26424. eCollection 2022 Jun.
Extra-nodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is uncommon and difficult to diagnose due to varied clinical presentations and endoscopic appearances masquerading as other pathology. Rarely, it has been associated with acute upper gastrointestinal (GI) bleeding. We report on a 60-year-old male who presented with an acute upper GI bleed and endoscopic findings suggestive of isolated gastric varices (GV), ultimately determined to be MALT lymphoma. Complete remission was achieved with radiation therapy, with no recurrence at a 12-month follow-up. This case highlights a unique clinical and endoscopic presentation of MALT lymphoma which providers should be aware of. We emphasize the use of endoscopic ultrasound (EUS) evaluation for accurate diagnosis.
黏膜相关淋巴组织(MALT)的结外边缘区淋巴瘤并不常见,由于临床表现多样且内镜表现易伪装成其他病理情况,故难以诊断。很少有病例与急性上消化道(GI)出血相关。我们报告了一名60岁男性,他因急性上消化道出血就诊,内镜检查结果提示孤立性胃静脉曲张(GV),最终确诊为MALT淋巴瘤。放疗后实现了完全缓解,12个月随访时无复发。该病例突出了MALT淋巴瘤独特的临床和内镜表现,临床医生应予以关注。我们强调使用内镜超声(EUS)评估以进行准确诊断。