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Infectious Complication in Relation to the Prophylactic Mesh Position: The PRIMA Trial Revisited: In Reply to Arora and Colleagues.
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World J Surg. 2021 Aug;45(8):2439-2446. doi: 10.1007/s00268-021-06120-5. Epub 2021 Apr 26.
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Interrupted sutures prevent recurrent abdominal fascial dehiscence: a comparative retrospective single center cohort analysis of risk factors of burst abdomen and its recurrence as well as surgical repair techniques.间断缝合可预防腹部筋膜反复裂开:一项关于腹部切口裂开及其复发的危险因素以及手术修复技术的单中心队列比较回顾性分析
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Life (Basel). 2021 Feb 11;11(2):138. doi: 10.3390/life11020138.
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Hernia. 2022 Apr;26(2):437-445. doi: 10.1007/s10029-020-02221-7. Epub 2020 May 25.
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J Am Coll Surg. 2020 Jan;230(1):76-87. doi: 10.1016/j.jamcollsurg.2019.09.010. Epub 2019 Oct 28.
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Hernia. 2020 Jun;24(3):441-447. doi: 10.1007/s10029-019-02060-1. Epub 2019 Oct 22.
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Prophylactic Intraperitoneal Onlay Mesh Following Midline Laparotomy-Long-Term Results of a Randomized Controlled Trial.剖腹手术后预防性腹腔内补片覆盖-一项随机对照试验的长期结果。
World J Surg. 2019 Jul;43(7):1669-1675. doi: 10.1007/s00268-019-04964-6.

在急诊剖腹术中预防性使用补片:长效合成可吸收网片有良好的早期效果。

Prophylactic onlay mesh at emergency laparotomy: promising early outcomes with long-acting synthetic resorbable mesh.

机构信息

Department of Surgery, Letterkenny University Hospital, Letterkenny, Ireland.

Intelligent Systems Research Centre, School of Computing, Engineering and Intelligent Systems, Ulster University, Derry, UK.

出版信息

ANZ J Surg. 2022 Sep;92(9):2218-2223. doi: 10.1111/ans.17925. Epub 2022 Aug 1.

DOI:10.1111/ans.17925
PMID:35912943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9540974/
Abstract

BACKGROUND

Careful surgical strategy is paramount in balancing the prevention of fascial dehiscence, incisional hernia (IH) and fear of additional mesh-related wound complications post-laparotomy. This study aims to review early outcomes of patients undergoing an emergency laparotomy with prophylactic TIGR® mesh, used to reduce early fascial dehiscence and potential subsequent IH.

METHOD

A retrospective, ethically approved review of 24 consecutive patients undergoing prophylactic TIGR® mesh placement during emergency laparotomies by a single surgeon between January 2017 and June 2021 at a University Hospital. A standardized approach included onlay positioning of the mesh, small-bite fascial closure, and a wound bundle. We recorded patient demographics, operative indications, findings, degree of peritonitis, postoperative complications, and mortality.

RESULT

The study included 24 patients; 16/24 (66.6%) were female and median age was 72.5 (range 31-86); 14/24 patients were ASA grade III or greater; 4/24 patients (16.6%) developed six complications and 3/6 occurred in a single patient. Complications included subphrenic abscess, seroma, intrabdominal hematoma, enterocutaneous fistula leading to deep wound infection and small bowel perforation. Five (20.8%) patients died in hospital; central venous catheter sepsis (n = 1), fungal septicaemia (n = 1) and multiorgan failure (n = 3). Surgical site infection and seroma rates were low, occurring in 2/24 patients (4% each).

CONCLUSION

This study has identified that prophylactic onlay mesh in patients undergoing an emergency laparotomy is not associated with significant wound infection or seroma when used with an active wound bundle. The wider use of TIGR® to prevent fascial dehiscence and potential long-term IH prevention should be considered.

摘要

背景

在平衡预防筋膜裂开、切口疝(IH)和担心剖腹术后与补片相关的额外伤口并发症时,精细的手术策略至关重要。本研究旨在回顾接受预防性 TIGR®补片的患者的早期结果,该补片用于减少早期筋膜裂开和潜在的后续 IH。

方法

对 2017 年 1 月至 2021 年 6 月期间,一位外科医生对 24 例连续接受预防性 TIGR®补片放置的患者进行了回顾性、伦理批准的回顾,这些患者在一家大学医院接受了紧急剖腹手术。标准方法包括补片的覆盖定位、小咬筋膜闭合和伤口束。我们记录了患者的人口统计学数据、手术指征、发现、腹膜炎程度、术后并发症和死亡率。

结果

该研究包括 24 例患者;24/24(66.6%)为女性,中位年龄为 72.5(范围 31-86);14/24 例患者为 ASA 分级 III 或更高;4/24 例(16.6%)发生 6 种并发症,其中 3 种发生在单个患者中。并发症包括膈下脓肿、血清肿、腹腔内血肿、肠外瘘导致深部伤口感染和小肠穿孔。5 例(20.8%)患者在医院死亡;中心静脉导管脓毒症(n=1)、真菌血症(n=1)和多器官衰竭(n=3)。手术部位感染和血清肿的发生率较低,分别为 2/24 例(各 4%)。

结论

本研究表明,在接受紧急剖腹手术的患者中使用预防性补片覆盖时,如果与主动伤口束一起使用,不会导致明显的伤口感染或血清肿。应考虑更广泛地使用 TIGR®来预防筋膜裂开和潜在的长期 IH 预防。