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[严重急性呼吸综合征冠状病毒2型疫苗在孕妇中的接受情况——一项横断面调查]

[SARS-Cov-2 vaccine's acceptance among pregnant women-A cross-sectional survey].

作者信息

Huré M, Peyronnet V, Sibiude J, Cazenave M G, Anselem O, Luton D, Vauloup-Fellous C, Deruelle P, Cordier A G, Benachi A, Mandelbrot L, Couffignal C, Pauphilet V, Vivanti A J, Picone O

机构信息

Assistance publique-Hôpitaux de Paris, AP-HP Nord, hôpital Louis-Mourier, service de gynécologie obstétrique, Colombes, France; Université Paris Cité, France.

Assistance publique-Hôpitaux de Paris, AP-HP Nord, hôpital Louis-Mourier, service de gynécologie obstétrique, Colombes, France.

出版信息

Gynecol Obstet Fertil Senol. 2022 Nov;50(11):712-720. doi: 10.1016/j.gofs.2022.07.004. Epub 2022 Jul 29.

Abstract

OBJECTIVE

SARS-CoV-2 is more likely to cause severe cases in pregnant women. They were part of the priority groups since April 2021 to benefit from SARS-CoV-2 vaccination before its extent to general population. This contribution aims to evaluate, in the postpartum period, the achievement of COVID-19 vaccination and factors associated in women during their pregnancy.

MATERIAL AND METHOD

Multicenter cross-sectional survey study conducted from September to December 2021 with online self-questionnaire. All postpartum patients hospitalized in one of the 6 participating maternity hospitals were invited to answer. The questionnaire asked patients about their demographic characteristics, vaccination modalities, vaccine tolerance, and their general perception of vaccination.

RESULTS

Of the 371 women who responded, the vaccination rate was 65.7% (IC95% [60.8-70.4]), whom 98.8% entirely during pregnancy. Associated factors with vaccination during pregnancy were older age, higher socio-professional category, and prior information provided by health professionals. Factors that appear to motivate vaccination were personal protection and protection of the newborn. Finally, main factors negatively influencing the vaccination process were the fear of vaccine side effects and the negative perception of vaccines in general.

DISCUSSION

Acceptability and information about the vaccine by health professionals is in constant improvement. Information campaigns should be continued to improve the acceptability of vaccination, in light of the accumulating data.

摘要

目的

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)更易导致孕妇出现重症病例。自2021年4月起,孕妇便属于优先接种群体,以便在SARS-CoV-2疫苗推广至普通人群之前从中受益。本研究旨在评估产后阶段孕妇的新冠疫苗接种情况以及相关影响因素。

材料与方法

2021年9月至12月开展多中心横断面调查研究,采用在线自填问卷形式。邀请了在6家参与研究的妇产医院之一住院的所有产后患者作答。问卷询问了患者的人口统计学特征、接种方式、疫苗耐受性以及她们对疫苗接种的总体看法。

结果

在371名回复者中,疫苗接种率为65.7%(95%置信区间[60.8 - 70.4]),其中98.8%在孕期全程接种。孕期接种疫苗的相关因素包括年龄较大、社会职业类别较高以及医护人员提供的预先信息。促使接种疫苗的因素是个人防护和对新生儿的保护。最后,对疫苗接种过程产生负面影响的主要因素是对疫苗副作用的恐惧以及对疫苗总体的负面看法。

讨论

医护人员对疫苗的可接受性和相关信息在持续改善。鉴于数据不断积累,应继续开展宣传活动以提高疫苗接种的可接受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30ca/9335352/6625ffa05cba/gr1_lrg.jpg

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