Tsiaousi Ioanna, Psarris Alexandros, Theodora Marianna, Antsaklis Panagiotis, Sindos Michael, Koutroumanis Pelopidas, Zacharakis Dimitris, Daskalakis George
1st Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
1st Department of Obstetrics and Gynecology, General Hospital of Athens "Alexandra", National and Kapodistrian University of Athens, Athens, GRC.
Cureus. 2024 Jul 1;16(7):e63562. doi: 10.7759/cureus.63562. eCollection 2024 Jul.
Pregnant women have been shown to have a higher risk of SARS-CoV-2 infection. Vaccination against the infection is the most effective strategy for preventing both severe disease and related complications. Nevertheless, vaccination hesitancy among pregnant women is an important issue affecting vaccine uptake and a major challenge for Public Health, as high rates of hesitancy can lead to complete refusal of vaccination, with health implications not only for the mother but also for the fetus. Based on the above, this review aims to capture the rates of vaccination against COVID-19 in pregnancy among European countries, from August 2020 to May 2022, as well as to highlight the predictive factors of its acceptance among pregnant women in these countries. The review of the available literature found that in Europe the acceptance of vaccination against COVID-19 among pregnant women varies with rates ranging from 21.3% to 87% for at least one dose and from 29.5% to 82.7%, for two doses of vaccine. Higher maternal education level, older age at pregnancy, previous vaccination against influenza and pertussis, positive attitude towards vaccines, and acceptance of vaccines during pregnancy are the most frequently reported positive predictors that are associated with higher vaccination rates. The information obtained from this study can contribute in the future, during epidemics or pandemics that may occur, to the development of targeted medical and communication strategies for the effective promotion of vaccination programs and the greatest possible coverage of the population, especially those belonging to vulnerable groups such as pregnant women.
已有研究表明，孕妇感染新冠病毒的风险更高。接种疫苗是预防重症疾病及相关并发症的最有效策略。然而，孕妇对接种疫苗的犹豫态度是影响疫苗接种率的一个重要问题，也是公共卫生面临的一项重大挑战，因为高犹豫率可能导致完全拒绝接种疫苗，这不仅会对母亲的健康产生影响，还会影响胎儿。基于上述情况，本综述旨在了解2020年8月至2022年5月期间欧洲各国孕妇接种新冠疫苗的比例，并突出这些国家孕妇接受疫苗接种的预测因素。对现有文献的综述发现，在欧洲，孕妇对新冠疫苗接种的接受程度各不相同，至少接种一剂疫苗的比例在21.3%至87%之间，接种两剂疫苗的比例在29.5%至82.7%之间。较高的母亲教育水平、怀孕时年龄较大、既往接种过流感疫苗和百日咳疫苗、对疫苗持积极态度以及在孕期接受疫苗接种是最常报告的与较高接种率相关的积极预测因素。本研究获得的信息在未来可能发生的流行病或大流行期间，有助于制定有针对性的医疗和宣传策略，以有效推广疫苗接种计划，并尽可能扩大人群覆盖范围，尤其是孕妇等弱势群体。
