Department of Pain, The Third Xiangya Hospital and Institute of Pain Medicine, Central South University, Changsha, China.
Hunan Key Laboratory of Brain Homeostasis, Central South University, Changsha, China.
Sci Rep. 2022 Aug 2;12(1):13285. doi: 10.1038/s41598-022-17627-9.
Percutaneous laser discectomy is one common and effective treatment for cervical radicular pain. Currently, the surgery is performed with blind cannulation technique, mainly relies on the experience of surgeon. However, it still remains unsafe and difficult to reach the target. As an alternative, ultrasound-guided cannulation provides visualization of important structures, thus increasing the precision and safety. The primary goal of this study is to report the detail of the ultrasound-guided technique in the percutaneous laser cervical discectomy. The secondary purpose is to evaluate the feasibility of the novel therapy. This is a single center, feasibility study conducted in one teaching hospital. Thirteen intervertebral discs in 9 patients presented with cervical radicular pain. Accuracy of the cannulation with ultrasonic guidance was confirmed by the anterior-posterior and lateral view of fluoroscopy. We compared the pain severity pre- and post-treatment with Visual Analogue Score (VAS), and functional improvement was assessed with the modified Macnab Criteria and Neck Disability Index (NDI) respectively. Ultrasonic short-axis was used to scan the cervical nerve root, and its transition was used to identify the distinct intervertebral space. Following the recognition of targeted cervical level, the ultrasound probe was moved medially for the visualization of the surface of the cervical vertebrae. In plane cannulation was then applied to avoid the injury of the vessels. The location of cannula was confirmed by the fluoroscopic imaging. Low-power laser was set for the cervical disc ablation in this cohort. The majority of the surgical sites maintained in the C5/6 level (38%), and 31% for the C6/7 level respectively. Despite the distinct cervical level, the tip of needle was properly placed near by the targeted intervertebral disc in all participants, which was confirmed by the imaging of fluoroscopy. We did not observe any obvious complications during the procedure. The mean VAS decreased from 7.6 ± 1.1 to 2.3 ± 2.7 one month after discharge, and 2.1 ± 2.6 at the last follow-up (median duration of nine months). All patients reported significant improvement of NDI up to last follow-up (p = 0.011). Meanwhile, the good to excellent rate was reported in 8 of 9 patients (89%) according to the modified Macnab Criteria. The finding of this feasibility assessment indicates the ultrasound-based cannulation technique is capable of guiding the cannulation for the percutaneous laser discectomy. It may facilitate identifying the corresponding site of cervical intervertebral disc and prevent the damage of vessel.
经皮激光椎间盘切除术是治疗颈椎神经根痛的一种常见且有效的方法。目前,该手术采用盲目套管技术,主要依赖于外科医生的经验。然而,这种方法仍然存在安全性和准确性的问题,难以达到治疗靶点。作为替代方法,超声引导套管技术可以提供重要结构的可视化,从而提高手术的精度和安全性。本研究的主要目的是报告经皮激光颈椎间盘切除术超声引导技术的详细信息。次要目的是评估这种新疗法的可行性。这是一项在一家教学医院进行的单中心可行性研究。9 名患者的 13 个椎间盘均因颈椎神经根痛接受了治疗。套管的准确性通过前后位和侧位透视进行了确认。我们使用视觉模拟评分(VAS)比较了治疗前后的疼痛严重程度,使用改良 Macnab 标准和颈部残疾指数(NDI)分别评估了功能改善情况。我们使用超声短轴扫描颈椎神经根,并通过其转变来识别不同的椎间空间。在识别目标颈椎水平后,将超声探头向内侧移动以显示颈椎表面。然后进行平面内套管,以避免血管损伤。套管的位置通过透视成像进行确认。在本队列中,我们使用低功率激光进行颈椎间盘消融。大多数手术部位位于 C5/6 水平(38%),C6/7 水平占 31%。尽管颈椎水平不同,但所有参与者的针尖均正确放置在目标椎间盘附近,这通过透视成像得到了确认。在手术过程中,我们未观察到任何明显的并发症。VAS 评分从出院时的 7.6±1.1 降至 1 个月后的 2.3±2.7,末次随访时为 2.1±2.6(中位数随访时间为 9 个月)。所有患者在末次随访时均报告了 NDI 的显著改善(p=0.011)。同时,根据改良 Macnab 标准,8/9 例(89%)患者报告了良好至优秀的结果。这项可行性评估的结果表明,基于超声的套管技术能够引导经皮激光椎间盘切除术的套管。它可以帮助识别颈椎椎间盘的相应部位,并防止血管损伤。