Department of Ophthalmology, GMC, Srinagar, Jammu and Kashmir, India.
Indian J Ophthalmol. 2022 Aug;70(8):2902-2905. doi: 10.4103/ijo.IJO_3178_21.
The purpose of this study was to assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliation glaucoma (PEXG), and to compare their RDW values with healthy controls.
40 patients with PEX, 40 with PEXG, and 80 control subjects were enrolled in this study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within one hour of blood collection.
RDW levels were significantly higher in patients with PEX and PEXG than in controls (P = 0.027 and P < 0.001, respectively). Furthermore, a significant difference was found in RDW values between PEXG and PEX groups (P = 0.016). RDW levels were gradually increased from control group to PEXG group (P < 0.001). Multivariate logistic regression analysis revealed that RDW was independently associated with the presence of PEX/PEXG (odds ratio 1.765, 95% confidence interval (CI) 1.095-2.867, P = 0.013).
We conclude that RDW may be a useful marker for predicting the presence of PEX and progression to PEXG.
本研究旨在评估红细胞分布宽度（RDW）在假性剥脱综合征（PEX）和假性剥脱性青光眼（PEXG）患者中的水平，并将其与健康对照组进行比较。
本研究纳入了 40 名 PEX 患者、40 名 PEXG 患者和 80 名对照组。对所有受试者进行了全面的眼科检查和全血细胞计数测量。全血细胞计数在采血后 1 小时内进行。
PEX 和 PEXG 患者的 RDW 水平明显高于对照组（P=0.027 和 P<0.001）。此外，PEXG 和 PEX 组之间的 RDW 值存在显著差异（P=0.016）。RDW 水平从对照组到 PEXG 组逐渐升高（P<0.001）。多变量 logistic 回归分析显示，RDW 与 PEX/PEXG 的存在独立相关（比值比 1.765，95%置信区间 1.095-2.867，P=0.013）。
我们得出结论，RDW 可能是预测 PEX 存在和进展为 PEXG 的有用标志物。
