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空气污染健康影响监测与健康风险评估技术及其应用——中国,2006 - 2019年

Air Pollution Health Impact Monitoring and Health Risk Assessment Technology and Its Application - China, 2006-2019.

作者信息

Han Jingxiu, Xu Dongqun, Xu Donggang, Yang Xu, Wang Qin, Chen Mingqing, Xia Wenrong, Xing Weiwei, Xu Chunyu, Liu Yue, Chang Junrui, Fu Wenliang, Hao Shuxin, Li Na, Dong Xiaoyan, Li Yunpu, Meng Congshen, Liu Jingyi

机构信息

China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.

Academy of Military Medical Sciences, Academy of Military Sciences, Beijing, China.

出版信息

China CDC Wkly. 2022 Jul 1;4(26):577-581. doi: 10.46234/ccdcw2022.125.

DOI:10.46234/ccdcw2022.125
PMID:35919456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9339357/
Abstract

Air pollution is a significant risk factor contributing to the burden of disease in China. Health risk assessment and management are important to reduce the impact of air pollution on public health. To help formulate standardized health risk assessment techniques, a series of studies were conducted from 2006 to 2019. Through systematic review, study of molecular mechanisms, epidemiological investigation, and health effect monitoring, the overall project established a monitoring and evaluation indicator system, a comprehensive information platform, software for automatic data cleaning, and standardized health risk assessment techniques. Technical specifications have been issued by the National Health Commission for promoting health risk assessments across China. This paper introduces the project, the research approach, its main research accomplishments, innovations, and public health significance, and describes directions for further research.

摘要

空气污染是导致中国疾病负担的一个重要风险因素。健康风险评估和管理对于减少空气污染对公众健康的影响至关重要。为了帮助制定标准化的健康风险评估技术,在2006年至2019年期间开展了一系列研究。通过系统综述、分子机制研究、流行病学调查和健康效应监测,该整体项目建立了监测与评估指标体系、综合信息平台、自动数据清理软件以及标准化的健康风险评估技术。国家卫生健康委员会已发布技术规范,以推动全国范围内的健康风险评估。本文介绍了该项目、研究方法、主要研究成果、创新点和公共卫生意义,并阐述了进一步研究的方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a3/9339357/cd9100585d34/ccdcw-4-26-577-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a3/9339357/e6f22964cac0/ccdcw-4-26-577-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a3/9339357/cd9100585d34/ccdcw-4-26-577-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a3/9339357/e6f22964cac0/ccdcw-4-26-577-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92a3/9339357/cd9100585d34/ccdcw-4-26-577-2.jpg

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First Technical Specifications for Health Risk Assessment of Ambient Air Pollution in China.
China CDC Wkly. 2021 Aug 13;3(33):706-709. doi: 10.46234/ccdcw2021.175.
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Research on the Establishment and Application of the Environmental Health Indicator System of Atmospheric Pollution in China.中国大气污染环境健康指标体系的建立与应用研究。
Bull Environ Contam Toxicol. 2021 Jan;106(1):225-234. doi: 10.1007/s00128-020-03084-5. Epub 2021 Jan 18.
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Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production.二异壬基邻苯二甲酸酯暴露通过激活 ACE/AT1R 轴和抑制 NO 生成导致血压升高。
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Environ Pollut. 2019 Apr;247:927-934. doi: 10.1016/j.envpol.2019.01.099. Epub 2019 Jan 31.
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Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice.比较邻苯二甲酸二乙酯和邻苯二甲酸二丁酯暴露对小鼠高血压的影响。
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Exposure to formaldehyde and diisononyl phthalate exacerbate neuroinflammation through NF-κB activation in a mouse asthma model.甲醛和邻苯二甲酸二异壬酯通过 NF-κB 激活加剧小鼠哮喘模型中的神经炎症。
Ecotoxicol Environ Saf. 2018 Nov 15;163:356-364. doi: 10.1016/j.ecoenv.2018.07.089. Epub 2018 Jul 27.
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