Sripairojthikoon W, Wyss J M
Am J Physiol. 1987 Jun;252(6 Pt 2):F957-63. doi: 10.1152/ajprenal.1987.252.6.F957.
Physiological studies are rapidly elucidating the function of the renal nerves; however, the anatomical location of the postganglionic cell bodies that supply the rat kidney has not been fully clarified. The origin of the sympathetic projection to the rat kidney was investigated in the present study by use of the fluorescent dye retrograde transport technique. Application of the dye to the renal nerves resulted in the fluorescent labeling of sympathetic cell bodies in paravertebral [thoracic (T) segment 6 through lumbar (L) segment 4] and prevertebral (renal, greater splanchnic, and celiac) ganglia and along the greater splanchnic nerve. Sympathetic neurons in all of these locations were round to fusiform in shape, 16-40 micron in diameter. They were dispersed uniformly throughout the paravertebral ganglia and splanchnic nerve, but in the celiac and greater splanchnic ganglia, cells projecting to the kidney were clustered near the origin of the renal nerve. In contrast to the cat, in which greater than 50% of the renal sympathetic innervation arises from the prevertebral ganglia, in the rat the majority (greater than 70%) of labeled renal sympathetic neurons were in the paravertebral ganglia, especially T12-L1. The distribution of renal sympathetic neurons in the paravertebral ganglia closely approximates the rostrocaudal distribution of renal afferent cell bodies in the dorsal root ganglia.
生理学研究正在迅速阐明肾神经的功能；然而，支配大鼠肾脏的节后细胞体的解剖位置尚未完全明确。在本研究中，使用荧光染料逆行运输技术研究了大鼠肾脏交感神经投射的起源。将染料应用于肾神经后，在椎旁（胸段6至腰段4）和椎前（肾、内脏大、腹腔）神经节以及沿内脏大神经的交感神经细胞体出现了荧光标记。所有这些位置的交感神经元呈圆形至梭形，直径为16 - 40微米。它们均匀地分散在椎旁神经节和内脏神经中，但在腹腔和内脏大神经节中，投射到肾脏的细胞聚集在肾神经起始处附近。与猫不同，猫中超过50%的肾交感神经支配来自椎前神经节，而在大鼠中，大多数（超过70%）标记的肾交感神经元位于椎旁神经节，尤其是胸12至腰1。椎旁神经节中肾交感神经元的分布与背根神经节中肾传入细胞体的前后分布非常接近。
