Lee Yeonhee, Yoo Kyung Don, Baek Seon Ha, Kim Yang Gyun, Kim Hyo Jin, Ryu Ji Young, Paek Jin Hyuk, Suh Sang Heon, Oh Se Won, Lee Jeonghwan, Jhee Jong Hyun, Suh Jin-Soon, Yang Eun Mi, Park Young Ho, Kim Yae Lim, Choi Miyoung, Oh Kook-Hwan, Kim Sejoong
Division of Nephrology, Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Republic of Korea.
Division of Nephrology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Kidney Res Clin Pract. 2022 Jul;41(4):393-411. doi: 10.23876/j.krcp.33.555. Epub 2022 Jul 28.
The Korean Society for Electrolyte and Blood Pressure Research, in collaboration with the Korean Society of Nephrology, has published a clinical practice guideline (CPG) document for hyponatremia treatment. The document is based on an extensive evidence-based review of the diagnosis, evaluation, and treatment of hyponatremia with the multidisciplinary participation of representative experts in hyponatremia with methodologist support for guideline development. This CPG consists of 12 recommendations (two for diagnosis, eight for treatment, and two for special situations) based on eight detailed topics and nine key questions. Each recommendation begins with statements graded by the strength of the recommendations and the quality of the evidence. Each statement is followed by rationale supporting the recommendations. The committee issued conditional recommendations in favor of rapid intermittent bolus administration of hypertonic saline in severe hyponatremia, the use of vasopressin receptor antagonists in heart failure with hypervolemic hyponatremia, and syndrome of inappropriate antidiuresis with moderate to severe hyponatremia, the individualization of desmopressin use, and strong recommendation on the administration of isotonic fluids as maintenance fluid therapy in hospitalized pediatric patients. We hope that this CPG will provide useful recommendations in practice, with the aim of providing clinical support for shared decision-making to improve patient outcomes.
韩国电解质与血压研究学会与韩国肾脏病学会合作，发布了一份低钠血症治疗的临床实践指南（CPG）文件。该文件基于对低钠血症诊断、评估和治疗的广泛循证综述，由低钠血症领域的代表性专家多学科参与，并在方法学家的支持下制定指南。本CPG基于八个详细主题和九个关键问题，包含12条推荐意见（两条关于诊断，八条关于治疗，两条关于特殊情况）。每条推荐意见开头均有依据推荐强度和证据质量分级的陈述。每条陈述后均有支持该推荐意见的理由。委员会发布了有条件推荐意见，支持在严重低钠血症时快速间歇性推注高渗盐水，在伴有高血容量性低钠血症的心力衰竭以及伴有中度至重度低钠血症的抗利尿激素分泌失调综合征中使用血管加压素受体拮抗剂，去氨加压素使用个体化，以及强烈推荐在住院儿科患者中使用等渗液作为维持液治疗。我们希望本CPG能在实践中提供有用的推荐意见，旨在为共同决策提供临床支持以改善患者预后。
