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血红素功能化杂化气凝胶电化学芯片用于 HO 的实时分析。

Hemin functionalized hybrid aerogel-enabled electrochemical chip for real-time analysis of HO.

机构信息

Key Laboratory for Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, PR China.

Chongqing Key Laboratory of Bio-perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing, 400044, PR China.

出版信息

Analyst. 2022 Aug 22;147(17):3822-3826. doi: 10.1039/d2an00524g.

DOI:10.1039/d2an00524g
PMID:35920103
Abstract

Herein, a novel hemin functionalized hybrid aerogel (He@GMA) is synthesized and applied to an electrochemical chip for real-time analysis of hydrogen peroxide (HO). The He@GMA shows a typical three-dimensional morphology and excellent peroxidase-like catalytic performance. The He@GMA-enabled electrochemical chip presents satisfactory performance for HO sensing with a low limit of detection (0.96 μM). Besides, the chip platform shows some advantages of less sample consumption and easier detection operation.

摘要

本文合成了一种新型的血红素功能化杂化气凝胶(He@GMA),并将其应用于电化学芯片中,用于实时分析过氧化氢(HO)。He@GMA 呈现出典型的三维形态和优异的过氧化物酶样催化性能。基于 He@GMA 的电化学芯片在 HO 传感方面表现出令人满意的性能,具有较低的检测限(0.96 μM)。此外,该芯片平台还具有样品消耗少、检测操作更简单等优点。

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