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埃塞俄比亚阿姆哈拉地区转诊医院收治的低出生体重新生儿的生存状况及死亡预测因素:回顾性随访研究

Survival Status and Predictors of Mortality Among Low Birthweight Neonates Admitted in Amhara Region Referral Hospitals of Ethiopia: Retrospective Follow-Up Study.

作者信息

Kebede Belete Fenta, Genie Yalemtsehay Dagnaw, Aregawi Desta Hailu, Tadele Behafta Afera

机构信息

School of midwifery, Institute of Health, Jimma University, Jimma, Ethiopia.

Department of nursing, Mizan-Tepi University, Mizan, Ethiopia.

出版信息

Health Serv Res Manag Epidemiol. 2022 Jul 29;9:23333928221117364. doi: 10.1177/23333928221117364. eCollection 2022 Jan-Dec.

DOI:10.1177/23333928221117364
PMID:35923501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9340404/
Abstract

BACKGROUND

Being born with low birthweight is a major determinant of perinatal, neonatal, and infant survival. Even though low birthweight-related neonatal mortality is high, there is an information gap regarding the survival status of low birthweight neonates and their predictors of mortality in Ethiopia.

OBJECTIVE

This study was conducted to assess the survival status and predictors of mortality among low birthweight neonates admitted to Amhara region referral hospitals in Ethiopia.

METHODS AND MATERIALS

A retrospective follow-up study was conducted on randomly selected low birthweight neonates admitted to the Amhara region referral hospital between January 01-2017 and December 30-2018. Data were entered into Epi-data 4.4.2.1 and exported to Stata 14 for cleaning and analysis. A cox regression model was used to analyze the data. Tables, charts, and text were used to report the results.

RESULTS

This study revealed that 35.2% of participants died with incidence rates of 37.86 per 1000 person-day observations (95%CI: 31.79-45.10). Sepsis (AHR:1.72(95% CI: 1.05-2.81), respiratory distress (AHR: 2.03 (95% CI:1.36-3.03), necrotizing enterocolitis (AHR: 2.47 (95% CI: 1.17-5.20), congenital anomalies (AHR:2.37 (95% CI: 1.36-4.13), extreme low birth weight (AHR:2.62 (95% CI:1.54-4.44) and prematurity (AHR: 2.55 (95% CI:1.10-5.92) were independent predictors of mortality.

CONCLUSION

Sepsis, respiratory distress, necrotizing enterocolitis, congenital anomalies, extremely low birth weight, and premature birth were the independent predictors of mortality. Therefore, it is better for all stakeholders to focus more on the early diagnosis and management of low birth weight neonates with the factors associated with mortality.

摘要

背景

低出生体重是围产期、新生儿期和婴儿期生存的主要决定因素。尽管与低出生体重相关的新生儿死亡率很高,但在埃塞俄比亚,关于低出生体重新生儿的生存状况及其死亡预测因素存在信息差距。

目的

本研究旨在评估埃塞俄比亚阿姆哈拉地区转诊医院收治的低出生体重新生儿的生存状况及其死亡预测因素。

方法和材料

对2017年1月1日至2018年12月30日期间随机选取的入住阿姆哈拉地区转诊医院的低出生体重新生儿进行回顾性随访研究。数据录入Epi-data 4.4.2.1并导出到Stata 14进行清理和分析。使用Cox回归模型分析数据。通过表格、图表和文本报告结果。

结果

本研究显示,35.2%的参与者死亡,发病率为每1000人日观察37.86例(95%置信区间:31.79 - 45.10)。败血症(风险比:1.72(95%置信区间:1.05 - 2.81))、呼吸窘迫(风险比:2.03(95%置信区间:1.36 - 3.03))、坏死性小肠结肠炎(风险比:2.47(95%置信区间:1.17 - 5.20))、先天性异常(风险比:2.37(95%置信区间:1.36 - 4.13))、极低出生体重(风险比:2.62(95%置信区间:1.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/9340404/d1305507d479/10.1177_23333928221117364-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/9340404/c5f85907f028/10.1177_23333928221117364-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/9340404/d1305507d479/10.1177_23333928221117364-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/9340404/c5f85907f028/10.1177_23333928221117364-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a52/9340404/d1305507d479/10.1177_23333928221117364-fig2.jpg

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