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颈部和/或肩部疼痛对自我报告的头痛治疗反应的影响——基于药房的患者调查结果

Impact of the Neck and/or Shoulder Pain on Self-reported Headache Treatment Responses - Results From a Pharmacy-Based Patient Survey.

作者信息

Gaul Charly, Gräter Heidemarie, Weiser Thomas, Michel Martin C, Lampert Anette, Plomer Manuel, Förderreuther Stefanie

机构信息

Headache Center Frankfurt, Frankfurt am Main, Germany.

Medical Consumer Healthcare, Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.

出版信息

Front Neurol. 2022 Jul 18;13:902020. doi: 10.3389/fneur.2022.902020. eCollection 2022.

Abstract

Neck and/or shoulder pain (NSP) frequently occurs together with headache. Therefore, we explored how patients with and without concomitant NSP differ in their baseline characteristics and in perceived treatment responses to an analgesic. An anonymous survey was performed among 895 patients with headache (735 self-reported tension-type headache [TTH]) who used an analgesic fixed-dose combination containing 400 mg ibuprofen and 100 mg caffeine as a non-prescription treatment. NSP was abundant among patients in our survey (60%) and was associated with >1 additional day of headache per month. Patients with NSP reported predominantly sedentary work more frequently than those without (40 vs. 29%); they also reported physical tension/poor posture as a perceived trigger factor more frequently (70 vs. 16%). The reported pain reduction was comparable in those with and without concomitant NSP regardless of whether assessed as mean pain rating (from about 6 to 1.5 on a 10-point rating scale), patients experiencing a ≥50% in pain reduction (89.6 vs. 88.8%) or becoming pain-free within 2 h (57 vs. 64%). However, recurrence of pain and use of another dose within the same day were more frequent with than without NSP. We conclude that concomitant NSP is frequent in patients with headache but does not substantially alter responses to a non-prescription medication.

摘要

颈部和/或肩部疼痛(NSP)常与头痛同时出现。因此,我们探究了伴有和不伴有NSP的患者在基线特征以及对镇痛药的治疗反应感知方面有何不同。我们对895例使用含400毫克布洛芬和100毫克咖啡因的固定剂量复方镇痛药进行非处方治疗的头痛患者(735例自我报告为紧张型头痛[TTH])进行了一项匿名调查。在我们的调查中,NSP在患者中很常见(60%),且与每月额外多1天以上的头痛相关。伴有NSP的患者比不伴有NSP的患者更频繁地报告主要从事久坐工作(40%对29%);他们也更频繁地报告身体紧张/姿势不良是可感知的触发因素(70%对16%)。无论评估为平均疼痛评分(10分制评分量表上从约6分降至1.5分)、疼痛减轻≥50%的患者比例(89.6%对88.8%)还是在2小时内疼痛消失的患者比例(57%对64%),伴有和不伴有NSP的患者报告的疼痛减轻情况相当。然而,伴有NSP的患者比不伴有NSP的患者疼痛复发和在同一天内使用另一剂药物的情况更频繁。我们得出结论,头痛患者中常伴有NSP,但这并不会显著改变对非处方药的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a4a/9339896/dfc5f7c879a3/fneur-13-902020-g0001.jpg

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