瘢痕疙瘩性痤疮与头皮回旋状毛囊角化病相关。
Acne Keloidalis Nuchae is Associated with Cutis Verticis Gyrata.
作者信息
Umar Sanusi, Lullo Jenna J, Carter Marissa J, Shitabata Paul K, Lee Delphine J
机构信息
Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Division of Dermatology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA.
出版信息
Clin Cosmet Investig Dermatol. 2022 Jul 26;15:1421-1427. doi: 10.2147/CCID.S369243. eCollection 2022.
PURPOSE
Both acne keloidalis nuchae (AKN) and cutis verticis gyrata (CVG) are scalp conditions predominantly affecting men. Both are characterized by dermal thickening and fibroblast hyperactivity. AKN typically occurs in the nuchal area, often involving the naturally occurring folds in the occipital region. The aim of this study was to determine the relationship between excessive scalp folding (CVG) and AKN.
PATIENTS AND METHODS
A total of 108 patients with AKN seen over 11 years from July 2009 and November 2020 were retrospectively evaluated. Patients with AKN concomitant with CVG were selected for analysis.
RESULTS
Seven of the 108 AKN patients had scalp-wide (widespread) AKN lesions, including 4 with CVG. In 3 of the 4 patients with concomitant AKN and CVG, the AKN was widespread, and its onset had preceded CVG by 1-2 years. In the fourth CVG patient, AKN lesions were confined to the nuchal area, and the CVG preceded AKN onset by several years. All patients were male, with a mean age of 35.8 years (overall) and 38.0 years (CVG group).
CONCLUSION
We describe a previously unreported relationship between widespread AKN and CVG, with the development of AKN preceding CVG formation.
目的
瘢痕疙瘩性痤疮（AKN）和头皮回状颅皮（CVG）均为主要影响男性的头皮疾病。二者均以真皮增厚和成纤维细胞活性亢进为特征。AKN通常发生在项部区域，常累及枕部自然形成的褶皱。本研究的目的是确定头皮过度折叠（CVG）与AKN之间的关系。
患者与方法
回顾性评估了2009年7月至2020年11月期间诊治的108例AKN患者。选取合并CVG的AKN患者进行分析。
结果
108例AKN患者中有7例存在全头皮（广泛）AKN病变，其中4例合并CVG。在4例合并AKN和CVG的患者中，有3例AKN病变广泛，且其发病比CVG早1 - 2年。在第4例CVG患者中，AKN病变局限于项部区域，且CVG比AKN发病早数年。所有患者均为男性，总体平均年龄为35.8岁，CVG组平均年龄为38.0岁。
结论
我们描述了一种此前未报道的广泛AKN与CVG之间的关系，即AKN的发生先于CVG的形成。
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