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从人脾脓肿中分离出的斯氏普罗威登斯菌CMC-4104的全基因组序列，含有多个NDM-1和PER-1碳青霉烯类耐药基因拷贝。

Complete Genome Sequence of Providencia stuartii CMC-4104, Isolated from a Human Splenic Abscess, Containing Multiple Copies of NDM-1 and PER-1 Carbapenem Resistance Genes.

作者信息

Rao Jayasimha, Stornelli Nicholas K, Everson Nathan A, McDaniel Lauren F, Gomez De La Espriella Mariana, Faulhaber Jason R, Todd S Michelle, Lahmers Kevin K, Jensen Roderick V

机构信息

Internal Medicine, Division of Infectious Disease, Carilion Medical Center, Roanoke, Virginia, USA.

Division of Infectious Disease, Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA.

出版信息

Microbiol Resour Announc. 2022 Sep 15;11(9):e0051422. doi: 10.1128/mra.00514-22. Epub 2022 Aug 4.

DOI:10.1128/mra.00514-22
PMID:35924937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9476899/
Abstract

We report the complete genome sequence of a clinical isolate of Providencia stuartii strain CMC-4104, isolated from a splenic abscess. Oxford Nanopore Technologies (ONT) and Illumina sequencing reads were assembled using Geneious to generate a 4,504,925-bp circular chromosome containing multiple copies of the NDM-1 and PER-1 genes in a genomic resistance island.

摘要

我们报告了从脾脓肿中分离出的斯氏普罗威登斯菌菌株CMC - 4104临床分离株的完整基因组序列。使用Geneious对牛津纳米孔技术公司（ONT）和Illumina测序读数进行组装，生成了一个4,504,925碱基对的环状染色体，该染色体在一个基因组抗性岛内含有多个NDM - 1和PER - 1基因拷贝。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ba/9476899/ccc07693a7f5/mra.00514-22-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ba/9476899/ccc07693a7f5/mra.00514-22-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ba/9476899/ccc07693a7f5/mra.00514-22-f001.jpg

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