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[一氧化碳中毒——新观点及基于当前指南的建议]

[Carbon monoxide intoxication-New aspects and current guideline-based recommendations].

作者信息

Fichtner A, Eichhorn L

机构信息

Notfall- und OP-Management, Kreiskrankenhaus Freiberg, Donatsring 20, 09599, Freiberg, Deutschland.

Anästhesie, Intensivmedizin und Schmerztherapie, Helios Klinikum Bonn/Rhein-Sieg, Bonn, Deutschland.

出版信息

Anaesthesiologie. 2022 Oct;71(10):801-810. doi: 10.1007/s00101-022-01149-0. Epub 2022 Jun 23.

DOI:10.1007/s00101-022-01149-0
PMID:35925170
Abstract

Carbon monoxide poisoning is a common and potentially life-threatening intoxication, showing an interindividual variety of unspecific symptoms as well as late neurological and other sequelae. Two new German guidelines (S2k guidelines diagnosis and treatment of carbon monoxide poisoning as well as S3 guidelines oxygen therapy in the acute care of adult patients) focus on current evidence-based information on diagnostics as well as therapeutic options with considerable uncertainty remaining. This review summarizes current information and presents a flow scheme for daily practical use.

摘要

一氧化碳中毒是一种常见且可能危及生命的中毒情况，表现出个体间各种非特异性症状以及迟发性神经和其他后遗症。两项新的德国指南（S2k一氧化碳中毒诊断和治疗指南以及S3成人急性护理中氧疗指南）聚焦于当前基于证据的诊断信息以及治疗选择，但仍存在相当大的不确定性。本综述总结了当前信息并提出了一个日常实际应用的流程方案。

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Effects of smoking on delayed neuropsychiatric sequelae in acute carbon monoxide poisoning: A prospective observational study.吸烟对急性一氧化碳中毒后迟发性神经精神后遗症的影响：一项前瞻性观察研究。
Medicine (Baltimore). 2021 May 21;100(20):e26032. doi: 10.1097/MD.0000000000026032.
2
Clinical predictors of delayed neurological sequelae in charcoal-burning carbon monoxide poisoning.烧炭导致一氧化碳中毒后发生迟发性神经后遗症的临床预测因素。
Am J Emerg Med. 2021 Oct;48:12-17. doi: 10.1016/j.ajem.2021.04.001. Epub 2021 Apr 3.
3
[The mechanism of hyperbaric oxygen regulating HMGB1 in the prevention and treatment of encephalopathy after acute CO poisoning].
[高压氧调控HMGB1在急性一氧化碳中毒后脑病防治中的机制]
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2020 Sep 20;38(9):641-645. doi: 10.3760/cma.j.issn.121094-20200109-00248.
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Management of Burns. Reply.烧伤的治疗。回复。
N Engl J Med. 2019 Sep 19;381(12):1189. doi: 10.1056/NEJMc1909342.
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Management of Osteomyelitis-Induced Massive Tibial Bone Defect by Monolateral External Fixator Combined with Antibiotics-Impregnated Calcium Sulphate: A Retrospective Study.单侧外固定架联合载抗生素硫酸钙治疗骨髓炎致胫骨骨缺损的疗效分析：一项回顾性研究。
Biomed Res Int. 2018 Dec 19;2018:9070216. doi: 10.1155/2018/9070216. eCollection 2018.
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Targeting optimal time for hyperbaric oxygen therapy following carbon monoxide poisoning for prevention of delayed neuropsychiatric sequelae: A retrospective study.针对一氧化碳中毒后高压氧治疗预防迟发性神经精神后遗症的最佳时间：一项回顾性研究。
J Neurol Sci. 2019 Jan 15;396:187-192. doi: 10.1016/j.jns.2018.11.025. Epub 2018 Nov 22.
7
Combined application of dexamethasone and hyperbaric oxygen therapy yields better efficacy for patients with delayed encephalopathy after acute carbon monoxide poisoning.地塞米松与高压氧疗法联合应用对急性一氧化碳中毒后迟发性脑病患者疗效更佳。
Drug Des Devel Ther. 2017 Feb 23;11:513-519. doi: 10.2147/DDDT.S126569. eCollection 2017.
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Pathophysiology, research challenges, and clinical management of smoke inhalation injury.烟雾吸入性损伤的病理生理学、研究挑战及临床管理
Lancet. 2016 Oct 1;388(10052):1437-1446. doi: 10.1016/S0140-6736(16)31458-1.
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In Reply: "Single Versus Multiple Hyperbaric Sessions for Carbon Monoxide Poisoning in a Murine Model".回复：“小鼠模型中一氧化碳中毒的单次与多次高压氧治疗疗程”
J Med Toxicol. 2017 Mar;13(1):129. doi: 10.1007/s13181-016-0590-4. Epub 2016 Oct 3.
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The use of hyperbaric oxygen therapy for carbon monoxide poisoning in Europe.欧洲高压氧疗法在一氧化碳中毒治疗中的应用。
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