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欧洲高压氧疗法在一氧化碳中毒治疗中的应用。

The use of hyperbaric oxygen therapy for carbon monoxide poisoning in Europe.

作者信息

Mutluoglu Mesut, Metin Suleyman, Uzun Günalp, Yildiz Senol

出版信息

Undersea Hyperb Med. 2016 Jan-Feb;43(1):49-56.

Abstract

BACKGROUND

The aim of this survey was to identify practice differences in the treatment of carbon monoxide (CO) poisoning with hyperbaric oxygen (HBO₂) therapy among centers in Europe.

MATERIALS AND METHODS

Using a commercial online survey website (surveymonkey.com), we created a questionnaire and invited the medical directors of hyperbaric centers in Europe by email to complete the survey.

RESULTS

Sixty-eight centers from 23 countries participated in the survey. While transient or prolonged unconsciousness was unanimously recognized as an indication for HBO₂ therapy, positive neurological findings, ECG suggesting acute ischemia and pregnancy were considered important indications of HBO₂ therapy in more than 95% of the centers. Twenty-three (44%) centers reported that they used carboxyhemoglobin (COHb) levels as a criterion for patient selection. Among responders, 39% (18/46) reported delivering a single session within the first 24 hours of CO poisoning, and nine (19%) reported delivering three sessions in the first day. The majority of the centers (52%) replied that they initially gave a single session per patient, which was repeated if symptoms persisted. We identified a total of 21 different HBO₂ profiles used in European centers.

CONCLUSION

Our results showed that the indications of CO poisoning for HBO₂ therapy are still not universally recognized. Additionally, HBO₂ therapy protocols used at European hyperbaric centers varied significantly, suggesting a need for more education regarding the published guidelines.

摘要

背景

本次调查旨在确定欧洲各中心在采用高压氧(HBO₂)疗法治疗一氧化碳(CO)中毒方面的实践差异。

材料与方法

我们利用一个商业在线调查网站(surveymonkey.com)创建了一份问卷,并通过电子邮件邀请欧洲高压氧中心的医学主任完成该调查。

结果

来自23个国家的68个中心参与了此次调查。虽然短暂或持续昏迷被一致认为是HBO₂疗法的适应证,但在超过95%的中心,阳性神经系统检查结果、提示急性缺血的心电图以及妊娠被视为HBO₂疗法的重要适应证。23个(44%)中心报告称,他们将碳氧血红蛋白(COHb)水平作为患者选择的标准。在回复者中,39%(18/46)报告在CO中毒后的头24小时内进行单次治疗,9个(19%)报告在第一天进行三次治疗。大多数中心(52%)回复称,他们最初为每位患者进行单次治疗,若症状持续则重复治疗。我们共确定了欧洲各中心使用的21种不同的HBO₂治疗方案。

结论

我们的结果表明,HBO₂疗法治疗CO中毒的适应证仍未得到普遍认可。此外,欧洲高压氧中心使用的HBO₂治疗方案差异显著,这表明需要针对已发表的指南开展更多教育。

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