Hartmann Wolfgang, Hardes Jendrik, Vieth Volker
Sektion für Translationale Pathologie, Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland.
Klinik für Tumororthopädie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Pathologie (Heidelb). 2022 Jul;43(4):319-329. doi: 10.1007/s00292-022-01079-z. Epub 2022 Jun 9.
The recent WHO classification of Bone Tumours (2020) has introduced several changes. Conceptionally, small round cell sarcomas are now summarized in a distinct chapter, acknowledging their occurrence in both, bone and soft tissue. In the light of new molecular findings some diagnostic categories, such as fibrohistiocytic tumors, have been abandoned, and a few new entities have been added to the classification. Finally, systematic changes were made with regard to the terminology employed in the classification of chondrogenic tumours, and modifications have been made with respect to the biological potential of some lesions. This article summarizes the major changes made, underscoring the elementary role of an interdisciplinary approach in the diagnosis and management of bone lesions.
世界卫生组织最近的骨肿瘤分类(2020年)引入了多项变化。从概念上讲,小圆细胞肉瘤现在被汇总在一个单独的章节中,承认它们在骨和软组织中均有发生。鉴于新的分子研究结果,一些诊断类别,如纤维组织细胞肿瘤,已被摒弃,并且有一些新的实体被添加到分类中。最后,对软骨源性肿瘤分类中使用的术语进行了系统性更改,并且对一些病变的生物学潜能进行了修改。本文总结了所做的主要更改,强调了跨学科方法在骨病变诊断和管理中的基本作用。