Yale Radiology and Biomedical Imaging, 330 Cedar Street, New Haven, CT, 06520, USA.
Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA, 98105, USA.
Skeletal Radiol. 2023 Aug;52(8):1443-1463. doi: 10.1007/s00256-023-04286-8. Epub 2023 Jan 19.
There are numerous bone tumors in the pediatric population, with imaging playing an essential role in diagnosis and management. Our understanding of certain bone tumors has rapidly evolved over the past decade with advancements in next-generation genetic sequencing techniques. This increased level of understanding has altered the nomenclature, management approach, and prognosis of certain lesions. We provide a detailed update of bone tumors that occur in the pediatric population with emphasis on the recently released nomenclature provided in the 5th edition of the World Health Organization Classification of Soft Tissue and Bone Tumours. We discuss other mesenchymal tumors of bone, hematopoietic neoplasms of bone, and WHO classification of undifferentiated small round cell sarcomas of bone. We have detailed osteogenic tumors and osteoclastic giant cell-rich tumors, as well as notochordal tumors, chondrogenic tumors, and vascular tumors of the bone in separate manuscripts.
儿科人群中有许多骨肿瘤，影像学在诊断和治疗中起着至关重要的作用。随着下一代基因测序技术的进步，我们对某些骨肿瘤的认识在过去十年中迅速发展。这种认识水平的提高改变了某些病变的命名、管理方法和预后。我们提供了儿科人群中发生的骨肿瘤的详细更新，重点介绍了在第五版世界卫生组织软组织和骨肿瘤分类中发布的最新命名。我们讨论了其他骨间叶肿瘤、骨造血性肿瘤和未分化小圆细胞肉瘤的世界卫生组织分类。我们详细介绍了成骨性肿瘤和破骨细胞丰富性巨细胞瘤，以及脊索瘤、软骨源性肿瘤和骨血管肿瘤，这些内容分别在单独的手稿中。
