Schulte Miriam, Hartmann Wolfgang
Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude D17, 48149, Münster, Deutschland.
Pathologie (Heidelb). 2023 Nov;44(6):348-356. doi: 10.1007/s00292-023-01235-z. Epub 2023 Oct 12.
Osseous lesions are rare; however, their incidence is increased in childhood and adolescence. The spectrum of osseous processes in this age group is limited, with benign lesions being much more prevalent than malignant tumors. For the differential diagnosis, it is essential to have in-depth knowledge of the more frequent bone diseases in children and adolescents. The current review presents these diseases based on the morphologic approach of the WHO classification, including giant cell-rich and cystic lesions, chondrogenic and bone-forming lesions [7]. Small round cell sarcomas which are now summarized in a separate chapter of the WHO classification have been described previously [12, 20].
骨病变较为罕见;然而,其发病率在儿童期和青春期有所增加。该年龄组的骨病变范围有限,良性病变远比恶性肿瘤更为常见。对于鉴别诊断而言,深入了解儿童和青少年中较常见的骨病至关重要。本综述基于世界卫生组织(WHO)分类的形态学方法介绍这些疾病,包括富含巨细胞和囊性病变、软骨源性和成骨性病变[7]。现在在WHO分类中单独成章的小圆细胞肉瘤此前已有描述[12, 20]。