Schüttler C, Jahns R, Prokosch U, Wach S, Wullich B
Central Biobank Erlangen (CeBE), Universitätsklinikum Erlangen und Medizinische Fakultät, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
Interdisziplinäre Biomaterial- und Datenbank der Medizinischen Fakultät Würzburg, Universitätsklinikum Würzburg, Würzburg, Deutschland.
Urologie. 2022 Jul;61(7):722-727. doi: 10.1007/s00120-022-01850-3. Epub 2022 May 30.
When we think of medical research, one intuitively associates it with the analysis of study data collected for a specific research question or with the secondary use of patient data from routine care. However, these are not the only sources for answering scientific questions. Especially for translational research, tissue and liquid samples such as blood, DNA or other body fluids provide essential insights into disease pathogenesis, development of new therapies and treatment decisions. Access to these biomedical materials is provided by so-called biobanks. By collecting, characterizing, documenting and, if necessary, processing human biospecimens in accordance with high quality standards, they can support research of the causes of diseases, early diagnosis and the targeted treatment of diseases, or make a significant contribution to the investigation of common diseases.
当我们想到医学研究时，人们直观地会将其与为特定研究问题收集的研究数据分析或常规护理中患者数据的二次使用联系起来。然而，这些并不是回答科学问题的唯一来源。特别是对于转化研究而言，诸如血液、DNA或其他体液等组织和液体样本能为疾病发病机制、新疗法的开发以及治疗决策提供重要见解。所谓的生物样本库提供了获取这些生物医学材料的途径。通过按照高质量标准收集、表征、记录并在必要时处理人类生物样本，它们能够支持对疾病病因的研究、疾病的早期诊断和靶向治疗，或者为常见疾病的调查做出重大贡献。
