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用于研究目的的转基因昆虫的迁移。

Movement of genetically modified insects for research purposes.

出版信息

Rev Sci Tech. 2022 May;41(1):100-106. doi: 10.20506/rst.41.1.3307.

DOI:10.20506/rst.41.1.3307
PMID:35925632
Abstract

Insects play a crucial role in research. Many laboratories are developing technologies to control insect vectors or agricultural pests by using genetic modifications that either reduce insect reproduction or increase refractoriness to disease transmission. Those tools include gene-drive elements that may spread such genetic traits in a selfsustaining and cost-effective manner. Since international research collaborations are nowadays routine, movement of genetically modified insects between laboratories under different regulatory jurisdictions is very common. This article describes the requirements and guidelines for transportation of genetically modified insects for research. The author draws upon the experience gained by an Italian laboratory, in its role as a research centre involved in shipments of wild and modified mosquitoes, within an international research consortium developing sustainable tools for malaria control.

摘要

昆虫在研究中起着至关重要的作用。许多实验室正在开发技术,通过遗传修饰来控制昆虫媒介或农业害虫,这些技术要么减少昆虫繁殖,要么增加对疾病传播的抵抗力。这些工具包括基因驱动元件,可以以自我维持和具有成本效益的方式传播这些遗传特征。由于如今国际研究合作是常规操作,因此在不同监管管辖区的实验室之间转移经过基因改造的昆虫非常常见。本文描述了用于研究的基因改造昆虫运输的要求和指南。作者借鉴了意大利一个实验室的经验,该实验室作为参与国际研究联盟的研究中心,该联盟正在开发可持续的疟疾控制工具,负责运输野生和改良蚊子。

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