Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, United States of America.
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Hempstead, NY, United States of America.
PLoS One. 2022 Aug 4;17(8):e0267505. doi: 10.1371/journal.pone.0267505. eCollection 2022.
To evaluate racial and ethnic differences in mortality among patients hospitalized with coronavirus disease 2019 (COVID-19) after adjusting for baseline characteristics and comorbidities.
This retrospective cohort study at 13 acute care facilities in the New York City metropolitan area included sequentially hospitalized patients between March 1, 2020, and April 27, 2020. Last day of follow up was July 31, 2020. Patient demographic information, including race/ethnicity and comorbidities, were collected. The primary outcome was in-hospital mortality.
A total of 10 869 patients were included in the study (median age, 65 years [interquartile range (IQR) 54-77; range, 18-107 years]; 40.5% female). In adjusted time-to-event analysis, increased age, male sex, insurance type (Medicare and Self-Pay), unknown smoking status, and a higher score on the Charlson Comorbidity Index were significantly associated with higher in-hospital mortality. Adjusted risk of hospital mortality for Black, Asian, Hispanic, multiracial/other, and unknown race/ethnicity patients were similar to risk for White patients.
In a large diverse cohort of patients hospitalized with COVID-19, patients from racial/ethnic minorities experienced similar mortality risk as White patients.
在调整基线特征和合并症后，评估新冠肺炎（COVID-19）住院患者的死亡率存在的种族和民族差异。
这项回顾性队列研究在纽约市大都市区的 13 家急性护理机构进行，纳入了 2020 年 3 月 1 日至 2020 年 4 月 27 日期间连续住院的患者。随访的最后一天是 2020 年 7 月 31 日。收集了患者的人口统计学信息，包括种族/民族和合并症。主要结局是院内死亡率。
共有 10869 名患者纳入本研究（中位数年龄为 65 岁[四分位距（IQR）54-77；范围 18-107 岁]；40.5%为女性）。在调整后的生存时间分析中，年龄增加、男性、保险类型（医疗保险和自付）、未知的吸烟状况和Charlson 合并症指数评分较高与更高的院内死亡率显著相关。与白人患者相比，黑人、亚洲人、西班牙裔、多种族/其他和未知种族/民族的患者住院死亡风险调整风险相似。
在 COVID-19 住院患者的大型多样化队列中，少数民族患者的死亡率与白人患者相似。
