Gambhir Mohit, Gamanagatti Shivanand, Sharma Raju, Manchanda Smita, Hemachandran Naren, Kriplani Alka, Dadhwal Vatsla, Malhotra Neena, Sharma J B
Department of Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
J Obstet Gynaecol India. 2022 Aug;72(Suppl 1):126-133. doi: 10.1007/s13224-021-01567-x. Epub 2021 Oct 6.
To study the efficacy and safety of uterine artery embolization in treatment of obstetric hemorrhage.
This ethically approved prospective study was conducted between November 2017 and October 2019, and written informed consent was obtained from all patients. Consecutive patients presenting with uncontrolled obstetric hemorrhage were evaluated. Fifty-three patients with uncontrolled bleeding underwent uterine artery embolization (UAE) and were followed up.
Spectrum of patients encountered in this study was arteriovenous malformations (AVMs) ( = 25), retained products of conception (RPOC) ( = 16), RPOC with secondary AVMs ( = 5), ectopic pregnancy ( = 5) and iatrogenic trauma to cervix or vagina ( = 2). A total of 57 UAE procedures were performed in these 53 patients as repeat sessions were required in four patients. Most common embolic agent used was polyvinyl alcohol (PVA) particles with gelfoam followed by cyanoacrylate glue as second most common agent. Technical success was achieved in 57 (100%) of 57 UAE procedures. Primary clinical success was achieved in 49 (92%) of 53 patients and secondary clinical success in 52 (98%) patients. Clinical failure was observed in one patient who underwent hysterectomy.
Uterine artery embolization is a safe and effective procedure in the management of uncontrolled obstetric hemorrhage.
研究子宫动脉栓塞术治疗产科出血的疗效和安全性。
本前瞻性研究于2017年11月至2019年10月进行,已获得伦理批准,并取得了所有患者的书面知情同意书。对连续出现无法控制的产科出血的患者进行评估。53例出血无法控制的患者接受了子宫动脉栓塞术(UAE)并进行了随访。
本研究中遇到的患者类型包括动静脉畸形(AVM)(25例)、妊娠物残留(RPOC)(16例)、合并继发性AVM的RPOC(5例)、异位妊娠(5例)以及宫颈或阴道医源性创伤(2例)。这53例患者共进行了57次UAE手术,因为有4例患者需要重复手术。最常用的栓塞剂是聚乙烯醇(PVA)颗粒加明胶海绵,其次是氰基丙烯酸酯胶,为第二常用的栓塞剂。57次UAE手术中有57次(100%)获得技术成功。53例患者中有49例(92%)获得初次临床成功,52例(98%)患者获得二次临床成功。1例接受子宫切除术的患者出现临床失败。
子宫动脉栓塞术是治疗无法控制的产科出血的一种安全有效的方法。