Abdullah Hafizah, Wong Yen Shen, Ibrahim Muhammad Amin, Natasya Musa Aisya, Jayaraman Thevaraajan, Mohd Zim Mohd Arif
National Heart Institute (IJN) Kuala Lumpur Malaysia.
Faculty Of Medicine University Teknologi MARA (UiTM) Sg Buloh Selangor Malaysia.
Respirol Case Rep. 2022 Aug 2;10(9):e01013. doi: 10.1002/rcr2.1013. eCollection 2022 Sep.
Cystic lung formation secondary to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was described during coronavirus disease pandemic, but with relatively low prevalence. A rare yet under-recognized complication is that these cystic areas may progress to bullae, cavities and pneumothorax. We reported two cases of ruptured bullae with pneumothorax following SARS-CoV-2 infection. Two patients were discharged following SARS-CoV-2 pneumonia, which did not require invasive mechanical ventilation (IMV). However, both patients presented again a month later with shortness of breath. Repeated computed tomography (CT) thorax showed development of bullous lung disease and pneumothorax. The first patient underwent surgical intervention whilst the second patient was treated conservatively. Development of bullous lung disease following SARS-CoV-2 infection is rare but may be associated with serious morbidity. Patients whose general condition permits should be offered surgical intervention whilst conservative management is reserved for non-surgical candidates.
在冠状病毒病大流行期间，曾有关于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染继发肺囊性形成的描述，但发生率相对较低。一种罕见但未得到充分认识的并发症是，这些囊性区域可能进展为肺大疱、空洞和气胸。我们报告了2例SARS-CoV-2感染后肺大疱破裂并气胸的病例。2例患者在SARS-CoV-2肺炎后出院，无需有创机械通气（IMV）。然而，2例患者均在1个月后再次出现气短症状。胸部重复计算机断层扫描（CT）显示出现了肺大疱疾病和气胸。第1例患者接受了手术干预，而第2例患者接受了保守治疗。SARS-CoV-2感染后肺大疱疾病的发生较为罕见，但可能伴有严重的发病率。一般状况允许的患者应接受手术干预，而保守治疗则适用于不适合手术的患者。
