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BabyDance润滑剂对精子参数的影响。

Effects of BabyDance Lubricant on Sperm Parameters.

作者信息

Rafaee Alemeh, Kakavand Kianoosh, Sodeifi Niloofar, Farrahi Faramarz, Sabbaghian Marjan

机构信息

Departments of Andrology, Reproductive Biomedicine Research Center, Royan Institute For Reproductive Biomedicine, ACECR, Tehran, Iran.

出版信息

J Hum Reprod Sci. 2022 Apr-Jun;15(2):133-137. doi: 10.4103/jhrs.jhrs_155_21. Epub 2022 Jun 30.

DOI:10.4103/jhrs.jhrs_155_21
PMID:35928467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9345282/
Abstract

BACKGROUND

Semen analysis is a common test conducted for diagnosing the cause of male infertility, so using an innocuous lubricant can be beneficial to reduce the semen collection difficulties.

AIMS

In this study, the effects of BabyDance™ lubricant gel, a paraben-free lubricant, on sperm parameters were investigated.

STUDY SETTING AND DESIGN

It was a prospective study and a total of 45 individuals were enrolled.

MATERIALS AND METHODS

First, the semen samples of 20 patients referred to Royan Research Institute were incubated with different concentrations of gel, and subsequently, the sperm motility and vitality were evaluated. In the second phase, 25 individuals who had a spermogram test were asked to apply the gel in the new semen examination.

STATISTICAL ANALYSIS

Obtained data were statistically analysed using SPSS software.

RESULTS

The results of the phase revealed that this gel does not affect the pH, sample colour, viability, total motility and progressive and non-progressive motility of spermatozoa at any concentration. The second phase results also represented no difference in spermatozoal characteristics with and without gel use. Moreover, 100% of the participants in the second phase were satisfied with the gel and recommended that to other patients.

CONCLUSION

It was concluded that this gel can be considered a harmless product to sperm and can be a beneficial option for clients referring to infertility centres that facilitate the semen collection process.

摘要

背景

精液分析是诊断男性不育原因的常见检查,因此使用无害润滑剂有助于减少精液采集困难。

目的

本研究调查了不含对羟基苯甲酸酯的润滑剂BabyDance™凝胶对精子参数的影响。

研究设置与设计

这是一项前瞻性研究,共纳入45名个体。

材料与方法

首先,将转诊至罗扬研究所的20名患者的精液样本与不同浓度的凝胶孵育,随后评估精子活力和存活率。在第二阶段,要求25名进行过精液检查的个体在新的精液检查中使用该凝胶。

统计分析

使用SPSS软件对获得的数据进行统计分析。

结果

第一阶段的结果显示,该凝胶在任何浓度下均不影响精子的pH值、样本颜色、存活率、总活力以及进行性和非进行性活力。第二阶段的结果也表明,使用和不使用凝胶时精子特征无差异。此外,第二阶段100%的参与者对该凝胶满意,并向其他患者推荐。

结论

得出的结论是,该凝胶可被视为对精子无害的产品,对于前往不育症中心的患者而言,它可能是一个有益的选择,有助于精液采集过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/9345282/7d080d4976e6/JHRS-15-133-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/9345282/57e0d109fa59/JHRS-15-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/9345282/7d080d4976e6/JHRS-15-133-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/9345282/57e0d109fa59/JHRS-15-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3284/9345282/7d080d4976e6/JHRS-15-133-g002.jpg

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Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century.全球不孕不育问题:21 世纪性别、生殖技术与全球运动的新思维
Hum Reprod Update. 2015 Jul-Aug;21(4):411-26. doi: 10.1093/humupd/dmv016. Epub 2015 Mar 22.
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In vitro effects of coital lubricants and synthetic and natural oils on sperm motility.性交润滑剂以及合成油和天然油对精子活动力的体外影响。
Fertil Steril. 2014 Apr;101(4):941-4. doi: 10.1016/j.fertnstert.2013.12.024. Epub 2014 Jan 23.
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The effects of vaginal lubricants on sperm function: an in vitro analysis.阴道润滑剂对精子功能的影响:一项体外分析。
J Assist Reprod Genet. 2014 Mar;31(3):333-9. doi: 10.1007/s10815-013-0168-x. Epub 2014 Jan 5.
5
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Fertil Steril. 2013 May;99(6):1581-6. doi: 10.1016/j.fertnstert.2013.01.116. Epub 2013 Mar 15.
6
Semen analysis and sperm function tests: How much to test?精液分析和精子功能测试:要进行多少项检测?
Indian J Urol. 2011 Jan;27(1):41-8. doi: 10.4103/0970-1591.78424.
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Factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics.具备良好女性特征的夫妇进行宫腔内人工授精周期时影响妊娠结局的因素
J Obstet Gynaecol. 2011 Jul;31(5):420-3. doi: 10.3109/01443615.2011.569780.
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Sperm toxicity of "nonspermicidal" lubricant and ultrasound gels used in reproductive medicine.生殖医学中使用的“非杀精剂”润滑剂和超声凝胶对精子的毒性。
Fertil Steril. 2011 Feb;95(2):835-6. doi: 10.1016/j.fertnstert.2010.09.011. Epub 2010 Oct 25.
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