Experimental carcinoma of the stomach in rats with chronic ulcers and following gastric surgery.

The data obtained did not prove the stimulating effect of experimental chronic ulcer on the induced carcinogenesis of the stomach in the rat. It is shown that some surgical procedures followed by a gastroduodenal reflux enhance the gastric carcinogenesis while the procedures without such a reflux do not reveal any modifying effect on stomach cancer. The results of this study together with data from literature may have some relevance to the treatment procedures of patients with gastric ulcers.