• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于褐藻聚糖的纳米材料及其在药物和生物医学应用中的多功能作用。

Fucoidan-based nanomaterial and its multifunctional role for pharmaceutical and biomedical applications.

机构信息

School of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.

State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.

出版信息

Crit Rev Food Sci Nutr. 2024;64(2):354-380. doi: 10.1080/10408398.2022.2106182. Epub 2022 Aug 5.

DOI:10.1080/10408398.2022.2106182
PMID:35930305
Abstract

Fucoidans are promising sulfated polysaccharides isolated from marine sources that have piqued the interest of scientists in recent years due to their widespread use as a bioactive substance. Bioactive coatings and films, unsurprisingly, have seized these substances to create novel, culinary, therapeutic, and diagnostic bioactive nanomaterials. The applications of fucoidan and its composite nanomaterials have a wide variety of food as well as pharmacological properties, including anti-oxidative, anti-inflammatory, anti-cancer, anti-thrombic, anti-coagulant, immunoregulatory, and anti-viral properties. Blends of fucoidan with other biopolymers such as chitosan, alginate, curdlan, starch, etc., have shown promising coating and film-forming capabilities. A blending of biopolymers is a recommended approach to improve their anticipated properties. This review focuses on the fundamental knowledge and current development of fucoidan, fucoidan-based composite material for bioactive coatings and films, and their biological properties. In this article, fucoidan-based edible bioactive coatings and films expressed excellent mechanical strength that can prolong the shelf-life of food products and maintain their biodegradability. Additionally, these coatings and films showed numerous applications in the biomedical field and contribute to the economy. We hope this review can deliver the theoretical basis for the development of fucoidan-based bioactive material and films.

摘要

褐藻胶是一种有前途的硫酸多糖,从海洋资源中分离出来,近年来由于其作为生物活性物质的广泛应用引起了科学家的兴趣。生物活性涂层和薄膜毫不奇怪地利用这些物质来创造新型的、烹饪用的、治疗用的和诊断用的生物活性纳米材料。褐藻胶及其复合材料的应用具有广泛的食品和药理学特性,包括抗氧化、抗炎、抗癌、抗血栓、抗凝、免疫调节和抗病毒特性。褐藻胶与其他生物聚合物如壳聚糖、藻酸盐、结冷胶、淀粉等的混合物显示出有前途的涂层和成膜能力。混合生物聚合物是改善其预期性能的推荐方法。本文综述了褐藻胶的基础知识和最新发展,以及基于褐藻胶的生物活性涂层和薄膜复合材料及其生物学特性。在本文中,基于褐藻胶的可食用生物活性涂层和薄膜表现出优异的机械强度,可以延长食品的保质期并保持其可生物降解性。此外,这些涂层和薄膜在生物医学领域有许多应用,并为经济做出了贡献。我们希望这篇综述能为基于褐藻胶的生物活性材料和薄膜的开发提供理论基础。

相似文献

1
Fucoidan-based nanomaterial and its multifunctional role for pharmaceutical and biomedical applications.基于褐藻聚糖的纳米材料及其在药物和生物医学应用中的多功能作用。
Crit Rev Food Sci Nutr. 2024;64(2):354-380. doi: 10.1080/10408398.2022.2106182. Epub 2022 Aug 5.
2
Recent Highlights in Sustainable Bio-Based Edible Films and Coatings for Fruit and Vegetable Applications.用于水果和蔬菜的可持续生物基可食用薄膜和涂层的近期亮点
Foods. 2024 Jan 19;13(2):318. doi: 10.3390/foods13020318.
3
Fucoidan, a brown seaweed polysaccharide in nanodrug delivery.褐藻糖胶,一种用于纳米药物递送的褐藻多糖。
Drug Deliv Transl Res. 2023 Oct;13(10):2427-2446. doi: 10.1007/s13346-023-01329-4. Epub 2023 Apr 3.
4
Algal Phycocolloids: Bioactivities and Pharmaceutical Applications.藻胶:生物活性与药物应用。
Mar Drugs. 2023 Jun 28;21(7):384. doi: 10.3390/md21070384.
5
Therapeutic Applications of Fucoidans and their Potential to Act Against COVID-19.岩藻多糖的治疗应用及其对抗 COVID-19 的潜力。
Curr Pharm Des. 2022;28(46):3671-3676. doi: 10.2174/1381612829666221207093215.
6
Bilayer coatings for extension of the shelf life of fish fillets: Incorporating seaweed sulfated polysaccharides in chitosan-alginate LbL structures.用于延长鱼片保质期的双层涂层:将海藻硫酸多糖整合到壳聚糖-海藻酸盐层层组装结构中。
Food Sci Nutr. 2024 Jan 3;12(4):2511-2522. doi: 10.1002/fsn3.3934. eCollection 2024 Apr.
7
Therapeutic activity of fucoidan and carrageenan as marine algal polysaccharides against viruses.岩藻依聚糖和角叉菜胶作为海洋藻类多糖的抗病毒治疗活性。
3 Biotech. 2022 Jul;12(7):154. doi: 10.1007/s13205-022-03210-6. Epub 2022 Jun 25.
8
Therapeutic Effects of Fucoidan: A Review on Recent Studies.褐藻糖胶的治疗效果:近期研究综述
Mar Drugs. 2019 Aug 21;17(9):487. doi: 10.3390/md17090487.
9
Seaweed Polysaccharide in Food Contact Materials (Active Packaging, Intelligent Packaging, Edible Films, and Coatings).食品接触材料(活性包装、智能包装、可食用薄膜和涂层)中的海藻多糖
Foods. 2021 Sep 3;10(9):2088. doi: 10.3390/foods10092088.
10
Physicochemical properties of fucoidan and its applications as building blocks of nutraceutical delivery systems.褐藻糖胶的理化性质及其作为营养输送系统构建模块的应用。
Crit Rev Food Sci Nutr. 2022;62(32):8935-8953. doi: 10.1080/10408398.2021.1937042. Epub 2021 Jun 16.

引用本文的文献

1
3D printed antibacterial and anti-inflammatory scaffold containing vanillin-loaded Soluplus nanomicelles for healing of infected wounds.用于感染伤口愈合的含香草醛负载的Soluplus纳米胶束的3D打印抗菌抗炎支架。
Sci Rep. 2025 Sep 1;15(1):32244. doi: 10.1038/s41598-025-18174-9.
2
From Sea to Therapy: Marine Biomaterials for Drug Delivery and Wound Healing.从海洋到治疗:用于药物递送和伤口愈合的海洋生物材料
Pharmaceuticals (Basel). 2025 Jul 23;18(8):1093. doi: 10.3390/ph18081093.
3
Recent advances in quantum dots: design principles, sensing mechanisms, and applications in food safety analysis.
量子点的最新进展:设计原理、传感机制及其在食品安全分析中的应用
Mikrochim Acta. 2025 Aug 22;192(9):614. doi: 10.1007/s00604-025-07410-8.
4
Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway.岩藻依聚糖通过AMPK/mTOR1/TFEB途径调节胰腺自噬,从而减轻NOD小鼠的自身免疫性糖尿病。
Iran J Basic Med Sci. 2024;27(1):31-38. doi: 10.22038/IJBMS.2023.68739.14981.
5
Assessing the multitargeted antidiabetic potential of three pomegranate peel-specific metabolites: An in silico and pharmacokinetics study.评估三种石榴皮特异性代谢产物的多靶点抗糖尿病潜力:一项计算机模拟和药代动力学研究。
Food Sci Nutr. 2023 Sep 13;11(11):7188-7205. doi: 10.1002/fsn3.3644. eCollection 2023 Nov.
6
Novel Fucoidan Pharmaceutical Formulations and Their Potential Application in Oncology-A Review.新型岩藻依聚糖药物制剂及其在肿瘤学中的潜在应用——综述
Polymers (Basel). 2023 Jul 29;15(15):3242. doi: 10.3390/polym15153242.
7
Nano-Sized Fucoidan Interpolyelectrolyte Complexes: Recent Advances in Design and Prospects for Biomedical Applications.纳米大小的褐藻糖胶聚电解质复合物:设计的最新进展及其在生物医学应用中的前景。
Int J Mol Sci. 2023 Jan 30;24(3):2615. doi: 10.3390/ijms24032615.
8
Starch-based environment friendly, edible and antimicrobial films reinforced with medicinal plants.以药用植物增强的淀粉基环保、可食用抗菌薄膜。
Front Nutr. 2023 Jan 10;9:1066337. doi: 10.3389/fnut.2022.1066337. eCollection 2022.
9
Thrombin and Factor Xa Hydrolysis of Chromogenic Substrates in the Presence of Sulfated Derivatives of Galactomannan and Galactoglucomannan Natural Gels.半乳甘露聚糖和半乳葡甘露聚糖天然凝胶的硫酸化衍生物存在下凝血酶和Xa因子对显色底物的水解作用
Pharmaceutics. 2022 Dec 1;14(12):2678. doi: 10.3390/pharmaceutics14122678.