Im James H B, Rodrigues Rebecca, Anderson Kelly K, Wilk Piotr, Stranges Saverio, Nicholson Kathryn
Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Lawson Health Research Institute, London, ON, Canada.
Age Ageing. 2022 Aug 2;51(8). doi: 10.1093/ageing/afac165.
multimorbidity has become an increasingly important issue for many populations around the world, including Canada. The objectives of this study were to estimate the prevalence of multimorbidity at first follow-up and to identify factors associated with multimorbidity using data from the Canadian Longitudinal Study on Aging (CLSA).
this study included 27,701 community-dwelling participants in the first follow-up of the CLSA. Multimorbidity was operationalised using two definitions (Public Health and Primary Care), as well as the cut-points of two or more chronic conditions (MM2+) and three or more chronic conditions (MM3+). The prevalence of multimorbidity was calculated at first follow-up and multivariable regression models were used to identify correlates of multimorbidity occurrence.
the prevalence of multimorbidity at first follow-up was 32.3% among males and 39.3% among females when using the MM2+ Public Health definition, whereas the prevalence was 67.2% among males and 75.8% among females when using the MM2+ Primary Care definition. Older age, lower alcohol consumption, lower physical activity levels, dissatisfaction with sleep quality, dissatisfaction with life and experiencing social limitations due to health conditions were significantly associated with increased odds of multimorbidity for both males and females, regardless of the definition of multimorbidity used.
various sociodemographic, behavioural and psychosocial factors are associated with multimorbidity. Future research should continue to examine how the prevalence of multimorbidity changes with time and how these changes may be related to specific risk factors. This future research should be supplemented with studies examining the longitudinal impacts of multimorbidity over time.
对于包括加拿大在内的世界许多人群而言,多重疾病已成为一个日益重要的问题。本研究的目的是利用加拿大老龄化纵向研究(CLSA)的数据,估计首次随访时多重疾病的患病率,并确定与多重疾病相关的因素。
本研究纳入了CLSA首次随访中的27701名社区居住参与者。多重疾病采用两种定义(公共卫生和初级保健)以及两种或更多慢性疾病(MM2+)和三种或更多慢性疾病(MM3+)的切点来进行操作定义。计算首次随访时多重疾病的患病率,并使用多变量回归模型来确定多重疾病发生的相关因素。
使用MM2+公共卫生定义时,首次随访时男性多重疾病的患病率为32.3%,女性为39.3%;而使用MM2+初级保健定义时,男性患病率为67.2%,女性为75.8%。无论使用何种多重疾病定义,年龄较大、饮酒量较低、身体活动水平较低、对睡眠质量不满意、对生活不满意以及因健康状况而经历社会限制,均与男性和女性多重疾病发生几率增加显著相关。
各种社会人口学、行为和心理社会因素与多重疾病相关。未来的研究应继续探讨多重疾病的患病率如何随时间变化,以及这些变化可能与特定风险因素有何关系。未来的这项研究应辅以考察多重疾病随时间的纵向影响的研究。