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中老年人群的睡眠行为与多种疾病的发生:来自加拿大老龄化纵向研究(CLSA)的发现

Sleep behaviours and multimorbidity occurrence in middle-aged and older adults: findings from the Canadian Longitudinal Study on Aging (CLSA).

作者信息

Nicholson Kathryn, Rodrigues Rebecca, Anderson Kelly K, Wilk Piotr, Guaiana Giuseppe, Stranges Saverio

机构信息

Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.

Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada; Department of Psychiatry, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.

出版信息

Sleep Med. 2020 Nov;75:156-162. doi: 10.1016/j.sleep.2020.07.002. Epub 2020 Jul 15.

DOI:10.1016/j.sleep.2020.07.002
PMID:32858355
Abstract

OBJECTIVE

Poor sleep quality and reduced sleep duration impact over half of older adults and are associated with adverse health outcomes, such as multiple chronic conditions (multimorbidity) and reduced longevity. Our objective was to examine the relationship between sleep behaviours and multimorbidity in Canada.

METHODS

We analysed data from the Canadian Longitudinal Study on Aging (CLSA), a cross-sectional national health survey of community-dwelling adults over the age of 45 years. A total of 30,011 participants had physiological and psychosocial data collected at baseline. Sleep measures included self-reported sleep duration (short: <6 h; normal: 6-8 h; long: >8 h) and sleep quality (dissatisfied/very dissatisfied; neutral; satisfied/very satisfied). Multimorbidity was defined using two definitions (public health and primary care) and two cut-points (2 or more and 3 or more chronic conditions).

RESULTS

Approximately 70% were living with multimorbidity using the primary care definition (females: 67.9%; males 57.9%), whereas approximately 30% were living with multimorbidity using the public health definition (females: 30.9%; males: 24.0%). Adjusted analyses indicated that the odds of multimorbidity were higher for participants who selfreported either short or long sleep duration, as well as dissatisfaction with sleep quality. Associations were stronger among younger age groups (45-54 years and 55-64 years).

CONCLUSIONS

Disrupted sleep may be a risk factor for multimorbidity across sexes and age groups. It is necessary to understand the potential impact of sleep on the risk of multimorbidity to inform both clinical and public health guidelines for the prevention and management of this major health issue.

摘要

目的

睡眠质量差和睡眠时间缩短影响着超过半数的老年人,并与不良健康后果相关,如多种慢性疾病(共病)和寿命缩短。我们的目的是研究加拿大睡眠行为与共病之间的关系。

方法

我们分析了加拿大老龄化纵向研究(CLSA)的数据,这是一项针对45岁以上社区居住成年人的全国性横断面健康调查。共有30,011名参与者在基线时收集了生理和心理社会数据。睡眠指标包括自我报告的睡眠时间(短:<6小时;正常:6 - 8小时;长:>8小时)和睡眠质量(不满意/非常不满意;中性;满意/非常满意)。共病使用两种定义(公共卫生和初级保健)以及两个切点(2种或更多和3种或更多慢性疾病)来定义。

结果

使用初级保健定义时,约70%的人患有共病(女性:67.9%;男性:57.9%),而使用公共卫生定义时,约30%的人患有共病(女性:30.9%;男性:24.0%)。调整分析表明,自我报告睡眠时间短或长以及对睡眠质量不满意的参与者患共病的几率更高。在较年轻年龄组(45 - 54岁和55 - 64岁)中关联更强。

结论

睡眠紊乱可能是不同性别和年龄组共病的一个危险因素。有必要了解睡眠对共病风险的潜在影响,以为预防和管理这一主要健康问题的临床和公共卫生指南提供依据。

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