在单纯收缩期高血压和单纯舒张期高血压中选择降压药物：ALLHAT 试验的二次分析。
Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial.
机构信息
Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
Department of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH.
出版信息
Am Heart J. 2022 Dec;254:30-34. doi: 10.1016/j.ahj.2022.07.006. Epub 2022 Aug 4.
Abstract
Despite broad treatment recommendations, there are limited published reports comparing the efficacy of different antihypertensive agents in patients with isolated systolic hypertension or isolated diastolic hypertension. This study was a secondary analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. We compared the use of chlorthalidone, amlodipine, or lisinopril on the primary outcome of combined coronary heart disease, stroke, or all-cause mortality in patients with isolated systolic hypertension or isolated diastolic hypertension.
摘要
尽管有广泛的治疗建议，但在单纯收缩期高血压或单纯舒张期高血压患者中，比较不同降压药物疗效的已发表报告有限。本研究是对抗高血压和降脂治疗预防心脏病发作试验的二次分析。我们比较了氯噻酮、氨氯地平或赖诺普利在单纯收缩期高血压或单纯舒张期高血压患者的主要复合终点（冠心病、卒中和全因死亡率）上的应用。
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本文引用的文献
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