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一项关于为慢性下背痛患者采用基于正念减压疗法提供依据的实验研究。

An experimental study to inform adoption of mindfulness-based stress reduction in chronic low back pain.

作者信息

Jones Salene M W, Sherman Karen J, Bermet Zoe, Palazzo Lorella G, Lewis Cara C

机构信息

Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA, 98109, USA.

Kaiser Permanente Washington Health Research Institute, Seattle, USA.

出版信息

Implement Sci Commun. 2022 Aug 6;3(1):87. doi: 10.1186/s43058-022-00335-w.

Abstract

BACKGROUND

Chronic low back pain is a common and sometimes disabling condition, and mindfulness-based stress reduction is recommended as a first line of therapy. This study tested whether different descriptions of mindfulness training altered based on influential intervention characteristics increased adoption intentions.

METHODS

People with chronic low back pain (n = 452) were randomized to review one of four mindfulness training descriptions in an online survey using a 2 × 2 factorial design. The first factor was evidence strength and quality with relative advantage (ER). The second factor was adaptability, trialability, complexity, and design quality and packaging (AD). Each factor had two levels: a description of standardized mindfulness training that described each intervention characteristic and a patient-centered description emphasizing flexibility and patient testimonials. The primary outcomes were intentions to try mindfulness training and practice mindfulness at home. Using structural equation modeling with a bootstrapped distribution, we tested six mediators, three of which are Theory of Planned Behavior predictors of intention-self-efficacy, norms, and attitudes- and the other three are predictors of adoption-feasibility, appropriateness, and acceptability.

RESULTS

Overall, the mindfulness training descriptions were not associated with an increase in intentions compared to the classic vignette (11/12 p's > 0.05). Most descriptions were unrelated to mediators except the classic ER with patient-centered AD was associated with higher self-efficacy/control and feasibility (p's ≤ 0.05; standardized effect range: 0.111-0.125). Self-efficacy/control (training standardized coefficient: 0.531, home: 0.686), norms (training: 0.303, home: 0.256), and attitudes (training: 0.316, home: 0.293) were all positively associated with intentions to adopt mindfulness training and home practice. Feasibility (training: 0.185; home: 0.293) and acceptability (training: 0.639; home: 0.554) were positively related to intentions to adopt mindfulness training. Appropriateness was related to intentions to adopt home practice (0.187) but not mindfulness training (0.100). None of the indirect effects from experimental group to intentions was significant (all p's > 0.05).

CONCLUSIONS

Self-efficacy/control and acceptability may be key mediators for increasing patient adoption of mindfulness. Because experimental manipulation did not substantially change intentions to adopt mindfulness, the presentation and delivery of MBSR may need to be tailored to the individual patient's needs rather than a specific format for chronic low back pain.

摘要

背景

慢性腰痛是一种常见且有时会导致残疾的病症,基于正念的减压疗法被推荐作为一线治疗方法。本研究测试了基于有影响力的干预特征对正念训练的不同描述是否会增加采用意愿。

方法

慢性腰痛患者(n = 452)被随机分组,在一项在线调查中使用2×2析因设计来查看四种正念训练描述中的一种。第一个因素是具有相对优势的证据强度和质量(ER)。第二个因素是适应性、可试验性、复杂性以及设计质量和包装(AD)。每个因素都有两个水平:一种是对标准化正念训练的描述,其中描述了每种干预特征;另一种是以患者为中心的描述,强调灵活性和患者推荐。主要结局是尝试正念训练的意愿以及在家中进行正念练习的意愿。使用具有自抽样分布的结构方程模型,我们测试了六个中介变量,其中三个是计划行为理论中意愿的预测因素——自我效能感、规范和态度,另外三个是采用的预测因素——可行性、适宜性和可接受性。

结果

总体而言,与经典案例相比,正念训练描述与意愿增加无关(12个p值中有11个大于(0.05))。除了经典的ER与以患者为中心的AD相结合与更高的自我效能感/控制感和可行性相关外(p值≤(0.05);标准化效应范围:(0.111 - 0.125)),大多数描述与中介变量无关。自我效能感/控制感(训练的标准化系数:(0.531),在家练习:(0.686)),规范(训练:(0.303),在家练习:(0.256))和态度(训练:(0.316),在家练习:(0.293))都与采用正念训练和在家练习的意愿呈正相关。可行性(训练:(0.185);在家练习:(0.293))和可接受性(训练:(0.639);在家练习:(0.554))与采用正念训练的意愿呈正相关。适宜性与在家练习的意愿相关((0.187)),但与正念训练的意愿无关((0.100))。从实验组到意愿的所有间接效应均不显著(所有p值均大于(0.05))。

结论

自我效能感/控制感和可接受性可能是增加患者采用正念的关键中介因素。由于实验操作并未实质性改变采用正念的意愿,基于正念的减压疗法的呈现和实施可能需要根据个体患者的需求进行调整,而不是采用针对慢性腰痛的特定形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/682c/9356436/17a1c0f4d40d/43058_2022_335_Fig1_HTML.jpg

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