Miniati Mario, Orrù Graziella, Paroli Mery, Cinque Maristella, Paolicchi Adriana, Gemignani Angelo, Perugi Giulio, Ciacchini Rebecca, Marazziti Donatella, Palagini Laura, Conversano Ciro
Department of Clinical and Experimental Medicine, University of Pisa, Via Roma, 67, Pisa, Italy E-mail:
Clin Neuropsychiatry. 2023 Oct;20(5):429-441. doi: 10.36131/cnfioritieditore20230505.
To investigate mindfulness traits/attitudes as protective factors against chronic pain related distress, depression and anxiety.
Fifty patients (25 with chronic non-oncologic pain-NOP; 25 with chronic oncologic pain-COP) were administered with the following scales: Visual Analogue Scale (VAS), Pain Disability Index (PDI), Italian Questionnaire for Pain (QUID), Perceived Stress Scale (PSS), State and Trait Anxiety Scale (STAY-y1 module), Beck Depression Inventory II (BDI-II), Pittsburgh Sleep Quality Index (PSQI), Psychological General Well Being Index (PGWBI), Mindful Attention Awareness Scale (MAAS).
MAAS value ≥ 4.38 was adopted as cut-off to compare '' (HM) vs. '' (NM) attitudes. Twenty-six patients (52%) scored ≥4.38, with no different distribution between NOP and COP. HM patients scored significantly lower than NM patients on PDI domain (4.5±3.2 vs. 6.4±2.8; p<.037), and on PSS (17.8±2.6 vs. 20.9±2.5; p<.0001), STAY-y1 (9.4±1.8 vs. 10.3±2.1; p<.0001), BDI-II (7.8±5.0 vs. 17.6±8.6; p<.0001) total scores. HM scored significantly higher than NM patients in all PGWBI domains. A multiple regression analysis was carried out to analyze the predictor variables of PGWB. The most complete model considered the variables MAAS, STAIy and VAS (F=42.21; p<.0001), that accounted for the 71.6% of PGWB variance. MAAS score was the only variable positively predicting for PGWB; STAIy and VAS scores predicted negatively.
Chronic pain patients with high levels of mindfulness attitudes experienced less distress, anxiety, depressive symptoms, and more physical and general wellbeing than patients with low levels of mindfulness attitudes.
研究正念特质/态度作为慢性疼痛相关困扰、抑郁和焦虑的保护因素。
对50名患者(25名患有慢性非肿瘤性疼痛-NOP;25名患有慢性肿瘤性疼痛-COP)进行以下量表评估:视觉模拟量表(VAS)、疼痛残疾指数(PDI)、意大利疼痛问卷(QUID)、感知压力量表(PSS)、状态和特质焦虑量表(STAY-y1模块)、贝克抑郁量表第二版(BDI-II)、匹兹堡睡眠质量指数(PSQI)、心理总体幸福感指数(PGWBI)、正念注意觉知量表(MAAS)。
采用MAAS值≥4.38作为切点来比较“高正念(HM)”与“低正念(NM)”态度。26名患者(52%)得分≥4.38,NOP和COP之间分布无差异。HM患者在PDI领域(4.5±3.2对6.4±2.8;p<0.037)、PSS(17.8±2.6对20.9±2.5;p<0.0001)、STAY-y1(9.4±1.8对10.3±2.1;p<0.0001)、BDI-II(7.8±5.0对17.6±8.6;p<0.0001)总分上显著低于NM患者。HM在所有PGWBI领域得分显著高于NM患者。进行多元回归分析以分析PGWB的预测变量。最完整的模型考虑了变量MAAS、STAIy和VAS(F=42.21;p<0.0001),它们解释了PGWB方差的71.6%。MAAS得分是唯一对PGWB有正向预测作用的变量;STAIy和VAS得分有负向预测作用。
与低正念态度的患者相比,高正念态度的慢性疼痛患者经历的困扰、焦虑、抑郁症状更少,身体和总体幸福感更高。