From the Department of Medicine, College of Medicine and Health Science, Sultan Qaboos University Hospital, Muscat, Oman.
From the Internal Medicine Program, Oman Medical Speciality Board, Al-Athaiba, Muscat, Oman.
Ann Saudi Med. 2022 Jul-Aug;42(4):269-275. doi: 10.5144/0256-4947.2022.269. Epub 2022 Aug 4.
Stroke mortality and related functional disability have been declining over the last two decades, but stroke continues to represent the second leading cause of cardiovascular death worldwide and the number one cause for acquired long-term disability.
Assess short- and long-term health outcomes after acute ischemic stroke and analyze factors associated with poor survival and functional outcomes.
Retrospective and survival analysis SETTING: Inpatient unit at a tertiary care referral hospital.
All patients admitted with acute ischemic stroke from 1 January 2017 to 31 August 2018 were included in the study. Functional status was assessed using the modified Rankin Scale (mRS). Other demographic and clinical variables were obtained from medical records. Data were analyzed by multivariable logistic regression, Cox proportional hazards, and the Kaplan-Meier method. Long-term follow-up data, including mortality and mRS was collected by follow-up phone call.
Functional dependency and factors associated with mortality.
110 with mean age of 67.0 (14.7) years; 59 patients (53.6%) were males.
Hypertension (75.5%), diabetes mellitus (54.6%), and dyslipidemia (29.1%) were common. Sixty-five patients (59.1%) had mRS >2 upon discharge including 18 patients (16.4%) who died during the hospital stay. The cumulative mortality rate was 25.4% (28/110) at 12 months and 30.0% (33/110) at 24 months. Twenty-nine stroke survivors (29/70, 41.4%) remained physically dependent (mRS >2) at the end of follow-up. Old age, atrial fibrillation, history of prior stroke, chronic kidney disease, and peripheral arterial disease were associated with increased mortality and functional dependence.
Patients in Oman with acute ischemic stroke tend to have a high comorbidity burden, and their functional dependency and mortality are higher compared to patients from developed countries. Therefore, evidence-based measures such as establishing stroke units are essential to improve the health outcomes of patients with acute ischemic stroke.
Retrospective at single center.
None.
在过去的二十年中，中风死亡率和相关功能障碍有所下降，但中风仍然是全球心血管死亡的第二大主要原因，也是获得性长期残疾的首要原因。
评估急性缺血性中风后的短期和长期健康结果，并分析与不良生存和功能结果相关的因素。
回顾性和生存分析。
三级转诊医院的住院病房。
研究纳入了 2017 年 1 月 1 日至 2018 年 8 月 31 日期间因急性缺血性中风入院的所有患者。采用改良 Rankin 量表（mRS）评估功能状态。其他人口统计学和临床变量从病历中获得。采用多变量逻辑回归、Cox 比例风险和 Kaplan-Meier 方法进行数据分析。通过随访电话收集长期随访数据，包括死亡率和 mRS。
功能依赖性和与死亡率相关的因素。
共纳入 110 例患者，平均年龄为 67.0（14.7）岁；59 例（53.6%）为男性。
高血压（75.5%）、糖尿病（54.6%）和血脂异常（29.1%）较为常见。65 例（59.1%）出院时 mRS>2，包括 18 例（16.4%）在住院期间死亡。12 个月时累积死亡率为 25.4%（28/110），24 个月时为 30.0%（33/110）。70 例存活的中风患者（29/70，41.4%）在随访结束时仍存在身体依赖性（mRS>2）。高龄、房颤、既往中风史、慢性肾脏病和外周动脉疾病与死亡率和功能依赖性增加相关。
阿曼的急性缺血性中风患者往往合并症负担较高，与发达国家的患者相比，他们的功能依赖性和死亡率更高。因此，需要采取循证措施，如建立中风单元，以改善急性缺血性中风患者的健康结果。
回顾性研究，且仅在单中心进行。
无。
