Aichi Prefectural University School of Nursing and Health, Togoku, Kamishidami, Moriyama-ku, Nagoya, 463-8502, Japan; Checkup Center, Daiyukai Daiichi Hospital, 1-6-12 Hagoromo, Ichinomiya, 491-8551, Japan.
Checkup Center, Daiyukai Daiichi Hospital, 1-6-12 Hagoromo, Ichinomiya, 491-8551, Japan.
Diabetes Metab Syndr. 2022 Aug;16(8):102584. doi: 10.1016/j.dsx.2022.102584. Epub 2022 Jul 31.
The aim of this study was to calculate the visceral fat area (VFA) based on the criteria for metabolic syndrome (MetS).
A multiple regression analysis was performed to determine the estimated VFA using data from Japanese participants (2315 men and 1684 women). Receiver operating characteristic curve (ROC) analyses were performed to determine the optimal estimated VFA cutoff for the diagnosis of central obesity. The cutoff was also applied to a second cohort to validate the model.
The estimated VFA was calculated using the MetS criteria, age, and body mass index (adjusted coefficient of determination = 0.682 for men and 0.726 for women). The area under the ROC curve for waist circumference, VFA, and estimated VFA were 0.669, 0.741, and 0.749, respectively, for men and 0.711, 0.787, and 0.803, respectively, for women. The optimal cutoffs for estimated VFA were 128.1 cm for men and 82.2 cm for women. Multivariate logistic regression for heart disease revealed that estimated VFA, rather than waist circumference, was associated with a high risk of heart disease.
The estimated VFA is a better index of central obesity than waist circumference and VFA for the diagnosis of MetS.
本研究旨在根据代谢综合征（MetS）标准计算内脏脂肪面积（VFA）。
对日本参与者（男性 2315 人，女性 1684 人）的数据进行多元回归分析，以确定估计的 VFA。进行受试者工作特征曲线（ROC）分析以确定用于诊断中心性肥胖的最佳估计 VFA 截断值。该截断值也应用于第二个队列进行模型验证。
使用 MetS 标准、年龄和体重指数（男性调整后的确定系数为 0.682，女性为 0.726）计算估计的 VFA。腰围、VFA 和估计 VFA 的 ROC 曲线下面积分别为男性 0.669、0.741 和 0.749，女性 0.711、0.787 和 0.803。男性估计 VFA 的最佳截断值为 128.1cm，女性为 82.2cm。用于心脏病的多变量逻辑回归表明，估计的 VFA 与心脏病的高风险相关，而不是腰围。
与腰围和 VFA 相比，估计的 VFA 是诊断 MetS 中心性肥胖的更好指标。
