Oka Rie, Kobayashi Junji, Yagi Kunimasa, Tanii Hideji, Miyamoto Susumu, Asano Akimichi, Hagishita Tomomi, Mori Mika, Moriuchi Tadashi, Kobayashi Makoto, Katsuda Shouji, Kawashiri Masa-aki, Nohara Atsushi, Takeda Yoshiyu, Mabuchi Hiroshi, Yamagishi Masakazu
Department of Internal Medicine, Hokuriku Central Hospital of Japan Mutual Aid Association of Public School Teachers, 123 Nodera, Oyabe, Toyama 932-8503, Japan.
Diabetes Res Clin Pract. 2008 Mar;79(3):474-81. doi: 10.1016/j.diabres.2007.10.016. Epub 2007 Nov 26.
In the new world-wide criteria for metabolic syndrome (MetS) by the International Diabetes Federation (IDF) in 2006, the Japanese is the only ethnicity in which the recommended waist circumference (WC) cutoff value is higher in women (>or=90cm) than in men (>or=85cm), and its validity appears to be controversial. We investigated the optimal cutoff points for the diagnosis of central obesity in Japanese men and women, using the receiver operating characteristic (ROC) curve analysis for both of WC and visceral fat area (VFA) in 1870 middle-aged Japanese. VFA was superior to WC and Body mass index (BMI) for discriminating the subjects with two or more nonadipose components of MetS. The optimal cutoff points of VFA and WC were 132.6cm(2) and 89.8cm for men and 91.5cm(2) and 82.3cm for women. The stratifications of MetS components more than 1.0 in average occurred more steeply by the accumulation of VFA in women than in men. In conclusion, setting the cutoff points of WC and VFA lower values in women than in men for the definition of central obesity is needed to identify the subjects with MetS in Japanese, as in other Asian populations.
在国际糖尿病联盟（IDF）2006年制定的新的全球代谢综合征（MetS）标准中，日本人是唯一一个女性推荐腰围（WC）临界值（≥90厘米）高于男性（≥85厘米）的种族，其有效性似乎存在争议。我们对1870名中年日本人进行了研究，通过对腰围和内脏脂肪面积（VFA）进行受试者工作特征（ROC）曲线分析，来探讨日本男性和女性中心性肥胖诊断的最佳切点。在区分患有两种或更多种非脂肪性代谢综合征成分的受试者方面，VFA优于腰围和体重指数（BMI）。男性VFA和腰围的最佳切点分别为132.6平方厘米和89.8厘米，女性分别为91.5平方厘米和82.3厘米。女性中，随着VFA的积累，平均超过1.0的代谢综合征成分分层比男性更为陡峭。总之，与其他亚洲人群一样，为了识别日本患有代谢综合征的受试者，需要将女性中心性肥胖定义中腰围和VFA的切点设定得低于男性。
