Unit for Environmental Sciences and Management, North-West University, South Africa and Department of Animal Health, Faculty of Natural and Agricultural Sciences, North-West University, South Africa.
Department of Animal Health, Faculty of Natural and Agricultural Sciences, North-West University, South Africa.
J S Afr Vet Assoc. 2022 Nov;93(2):63-69. doi: 10.36303/JSAVA.83. Epub 2022 Jun 16.
Rodents are key carriers and reservoirs of various pathogens of public health importance to both human and animal diseases. This research was carried out in order to identify the selected pathogens, namely, and from rats that inhabit the poultry houses. A total of 154 samples from captured rats were examined for the zoonotic bacterial pathogens, of which 3.3%, 29.9% and 20.7% were harbouring , and , respectively. A total of 14 isolates expressed presence of H gene, of which eight and five were positive for and , respectively. For , 68 isolates were positive for A and other genes including with 26 (38%), I 2 (18%), C 14 (20%), A 28 (41%), L 43 (63%), L 31 (46%) and C 38 (56%). For , the gene was the most prevalent (62 [42%]), followed by the gene, which was only detected in 21 (14%) isolates, while gene was not detected in any of the samples. This study shows that zoonotic pathogens with virulence genes are circulating in rodents from selected chicken farms in the North West Province of South Africa. Rodents must therefore be regarded as important carriers of zoonotic pathogens that can potentially infect both humans and animals.
啮齿动物是人类和动物疾病中具有公共卫生重要性的各种病原体的主要携带者和储存库。这项研究旨在从栖息在禽舍中的老鼠中鉴定出选定的病原体，即 和 。从捕获的老鼠中总共检查了 154 个样本，以检测人畜共患的细菌病原体，其中 3.3%、29.9%和 20.7%分别携带 、 和 。共有 14 个分离株表达了 H 基因，其中 8 个和 5 个分别对 和 呈阳性。对于 ，68 个分离株对 A 和其他基因（包括 ）呈阳性，其中 26 个（38%）、I 2 （18%）、C 14 （20%）、A 28 （41%）、L 43 （63%）、L 31 （46%）和 C 38 （56%）。对于 ， 基因最为普遍（62 [42%]），其次是 基因，仅在 21 个（14%）分离株中检测到，而 基因在任何样本中均未检测到。本研究表明，具有毒力基因的人畜共患病原体在南非西北省选定的鸡场的啮齿动物中传播。因此，啮齿动物必须被视为可能感染人类和动物的人畜共患病原体的重要携带者。
