Khan Arshan, Gidda Harish, Murphy Nicholas, Alshanqeeti Shatha, Singh Inderpal, Wasay Abdul, Haseeb Muhammad
Internal Medicine, Ascension St. John Hospital, Detroit, USA.
Internal Medicine, Wayne State University School of Medicine, Detroit, USA.
Cureus. 2022 Jul 6;14(7):e26616. doi: 10.7759/cureus.26616. eCollection 2022 Jul.
Fournier's gangrene (FG) is necrotizing fasciitis that affects the penis, scrotum, or perineum. Males are more likely to get affected by this disease. The most common predisposing risk factors are diabetes, alcoholism, hypertension, smoking, and immunosuppressive disorders. FG is a polymicrobial infection caused by both aerobic and anaerobic bacteria. The most common aerobic organisms are , , , , and . The most common anaerobic organisms are , , and . The disease carries high mortality and morbidity, so timely diagnosis and treatment are of utmost importance. Here, we report a case of a 61-year-old male with a medical history significant for benign prostatic hyperplasia (BPH), who presented to our hospital with fever, watery diarrhea, and painful swelling of the scrotum and penis. The patient was started on piperacillin-tazobactam, vancomycin, and clindamycin. A computed tomography scan of the pelvis showed prostatic enlargement, edema of the penis and scrotum, and air collection within the corpus cavernosum. The patient underwent multiple surgical debridements of the glans penis. Patient wound cultures were positive for , , and . As mentioned earlier, FG is common in diabetic and immunocompromised patients, and infection is usually polymicrobial. Our patient was immunocompetent and his cultures grew atypical organisms.
福尼尔坏疽(FG)是一种坏死性筋膜炎,累及阴茎、阴囊或会阴。男性更易患此病。最常见的诱发危险因素是糖尿病、酗酒、高血压、吸烟和免疫抑制性疾病。FG是一种由需氧菌和厌氧菌引起的混合感染。最常见的需氧菌是 、 、 、 和 。最常见的厌氧菌是 、 和 。该病死亡率和发病率高,因此及时诊断和治疗至关重要。在此,我们报告一例61岁男性病例,其有良性前列腺增生(BPH)病史,因发热、水样腹泻以及阴囊和阴茎疼痛性肿胀前来我院就诊。患者开始使用哌拉西林 - 他唑巴坦、万古霉素和克林霉素治疗。骨盆计算机断层扫描显示前列腺肿大、阴茎和阴囊水肿以及海绵体内积气。患者接受了多次阴茎头手术清创。患者伤口培养结果显示 、 和 呈阳性。如前所述,FG在糖尿病患者和免疫功能低下患者中常见,且感染通常为混合菌感染。我们的患者免疫功能正常,其培养结果显示为非典型微生物。