Warraich Muhammad Sheharyar, Attar Bashar, Khalid Shazaq
Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Gastroenterology and Hepatology, Rush University Medical Center, Chicago, USA.
Cureus. 2022 Jul 3;14(7):e26535. doi: 10.7759/cureus.26535. eCollection 2022 Jul.
Eosinophilic granulomatosis with polyangiitis (EGPA) is a small- and medium-vessel vasculitis that majorly involves the respiratory tract but can potentially involve any organ system of the body. Involvement of the gastrointestinal (GI) tract can present on a spectrum. We present an interesting case of a 44-year-old man with a history of asthma and sinusitis who presented with non-specific GI symptoms and weight loss. The patient got diagnosed with EGPA. Endoscopic workup of the GI complaints revealed gastric ulcer and erosions of the upper GI tract. Biopsies of the lesions demonstrated eosinophilic infiltration suggestive of EGPA. This report represents a rare case of GI involvement of EGPA that could be histologically confirmed.
嗜酸性肉芽肿性多血管炎(EGPA)是一种中小血管血管炎,主要累及呼吸道,但也可能累及身体的任何器官系统。胃肠道(GI)受累情况呈多样化。我们报告了一例有趣的病例,一名44岁有哮喘和鼻窦炎病史的男性,出现非特异性胃肠道症状和体重减轻。该患者被诊断为EGPA。对胃肠道不适进行的内镜检查发现胃溃疡和上消化道糜烂。病变活检显示嗜酸性浸润,提示为EGPA。本报告代表了一例罕见的经组织学证实的EGPA胃肠道受累病例。