Ghasemi Negin, Yavari Hamidreza, Samiei Mohammad, Asl Aminabadi Naser, Dabbaghi Tabriz Fatemeh, Taheri Samra, Davoudi Paria
Dental and Periodontal Research Center, Department of Endodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Pediatric Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
J Dent Res Dent Clin Dent Prospects. 2022 Winter;16(1):40-44. doi: 10.34172/joddd.2022.007. Epub 2022 May 29.
The bond strength of the materials used as a cervical barrier in the pulp regeneration is essential for the success of treatment. This study aimed to evaluate the effects of triple antibiotic paste (TAP), double antibiotic paste (DAP), and simvastatin as intracanal medicaments on the dislodgement resistance of mineral trioxide aggregate (MTA) and calcium-enriched mixture (CEM). A total of 160 extracted human single-rooted teeth were selected, and root canal preparation was carried out. The teeth in each group were randomly divided into four subgroups: TAP, DAP, simvastatin, and the control group (without intracanal medicament). Four weeks after placing the medicaments, it was removed by sodium hypochlorite, and MTA and CEM were placed in the coronal third of the root canals. After a week, 2-mm-thick dentin disks were prepared from the coronal third of the roots, and the push-out test was performed using a universal testing machine. The data were analyzed using two-way ANOVA and independent -test at a significance level of 0.05. Regardless of the intracanal medicament, there was no significant difference between the overall bond strength of MTA (59.3±10 MPa) and CEM (55.8±11 MPa) (=0.6). Furthermore, there were no significant differences in bond strength between the two intracanal medicament groups and the control group (>0.05). Under the limitations of the current study, DAP, simvastatin, and TAP, as intracanal medicaments, did not adversely affect the push-out bond strength of CEM and MTA.
用作牙髓再生中根管口屏障的材料的粘结强度对于治疗的成功至关重要。本研究旨在评估三联抗生素糊剂（TAP）、双联抗生素糊剂（DAP）和辛伐他汀作为根管内药物对矿物三氧化物凝聚体（MTA）和富钙混合物（CEM）抗脱位性的影响。共选取160颗拔除的人单根牙，进行根管预备。每组牙齿随机分为四个亚组：TAP组、DAP组、辛伐他汀组和对照组（无根管内药物）。放置药物四周后，用次氯酸钠将其去除，然后将MTA和CEM放置在根管的冠三分之一处。一周后，从牙根的冠三分之一处制备2毫米厚的牙本质盘，并用万能试验机进行推出试验。数据采用双向方差分析和独立样本t检验进行分析，显著性水平为0.05。无论根管内使用何种药物，MTA（59.3±10 MPa）和CEM（55.8±11 MPa）的总体粘结强度之间均无显著差异（P=0.6）。此外，两个根管内药物组与对照组之间的粘结强度也无显著差异（P>0.05）。在本研究的局限性下，DAP、辛伐他汀和TAP作为根管内药物，对CEM和MTA的推出粘结强度没有不利影响。
