Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, International Campus, Mahan St, Navab Highway, Tehran, Iran.
General Dentist, Tehran University of Medical Sciences, Tehran, Iran.
BMC Oral Health. 2022 May 25;22(1):207. doi: 10.1186/s12903-022-02213-2.
This study aimed to assess the effect of different commercially used calcium hydroxide [Ca(OH)], the mixture of Ca(OH) + silver nanoparticles (AgNPs), and other intracanal medicaments on dislodgement resistance of mineral trioxide aggregate (MTA) to root canal dentin in short- and long-term application.
Forty-six human single-rooted maxillary teeth were sectioned horizontally at mid-root into 1 mm thick slices. The lumen of the slices was standardized using #2-#5 Gates Glidden drills to a standard diameter of 1.3 mm in all samples. After smear layer removal, the samples were randomly divided into eight groups (n = 20) and treated with the following medicaments; Ca(OH) paste, Calcipex, Metapex, chlorhexidine (CHX), Ca(OH)/CHX paste, Ca(OH)/AgNPs, triple antibiotic paste and control group (normal saline). The samples were then incubated at 37 °C with 100% humidity for 1 week. Next, half of the teeth in each group (n = 10) were removed from the incubator and washed in an ultrasonic bath. ProRoot MTA was placed in the canal lumen and the samples were incubated at 37 °C and 100% humidity for 48 h to allow complete setting of MTA. The remaining half in each group (n = 10) was subjected to the same process after 1 month of application of medicaments. The dislodgement resistance of MTA to root dentin was measured. The data were analysed using two-way ANOVA and Tukey's post hoc test.
No significant difference was noted in dislodgement resistance of samples after 1 week and 1 month in any group (P > 0.05). The only significant difference was noted between the control and CHX groups and the higher dislodgement resistance was recorded in the CHX group (P = 0.006). No other significant differences were noted between the groups (P > 0.05).
Duration of application and the type of intracanal medicament do not affect the dislodgement resistance of MTA to root dentin. Although there was no statistically significant difference in the dislodgment resistance of MTA between the medicaments, CHX had a promising effect.
本研究旨在评估不同市售的氢氧化钙[Ca(OH)]、Ca(OH)+银纳米粒子（AgNPs）混合物以及其他根管内药物对 MTA 与根管牙本质固位力的影响，分为短期和长期应用。
将 46 颗上颌单根人牙在根管中部水平切成 1mm 厚的切片。所有样本的管腔均用 #2-#5 Gates Glidden 锉标准化至 1.3mm 的标准直径。去除玷污层后，将样本随机分为 8 组（n=20），分别用以下药物处理：Ca(OH) 糊剂、Calcipex、Metapex、洗必泰（CHX）、Ca(OH)/CHX 糊剂、Ca(OH)/AgNPs、三联抗生素糊剂和对照组（生理盐水）。然后将样本在 37°C 和 100%湿度下孵育 1 周。接着，每组的一半样本（n=10）从孵育器中取出，在超声浴中清洗。将 ProRoot MTA 置于根管腔中，将样本在 37°C 和 100%湿度下孵育 48h，以使 MTA 完全凝固。每组的另一半样本（n=10）在药物应用 1 个月后进行相同的处理。测量 MTA 与根管牙本质的固位力。使用双因素方差分析和 Tukey 事后检验对数据进行分析。
任何组别的样本在 1 周和 1 个月后的固位力均无显著差异（P>0.05）。仅在对照组和 CHX 组之间观察到显著差异，CHX 组的固位力更高（P=0.006）。各组之间无其他显著差异（P>0.05）。
应用时间和根管内药物的类型不会影响 MTA 与根管牙本质的固位力。虽然 MTA 的固位力在药物之间没有统计学上的显著差异，但 CHX 具有良好的效果。
