Franceschi Debora, Di Gianfilippo Riccardo, Rubino Ida, Serni Lapo, Pini Prato Giovan Paolo
Department of Experimental and Clinical Medicine University of Florence Florence Italy.
Department of Periodontics and Oral Medicine The University of Michigan School of Dentistry Ann Arbor Michigan USA.
Clin Case Rep. 2022 Aug 3;10(8). doi: 10.1002/ccr3.6056. eCollection 2022 Aug.
Herpes Simplex Virus type 1 (HSV-1) is a very common infection often localized in the mucocutaneous junction of the lip. Rarely, it could be detected also in periodontal tissues, associated with an elevated risk of periodontal disease progression and gingival recessions. Recently, HSV-1 and numerous co-infections have been reported in literature associated with the Coronavirus and subsequent COVID-19 disease. This report illustrates a case of HSV-1 in a patient with Covid-19 infection, showing the presence of ulcers and vesicles on the gingival margin of maxillary teeth associated with soreness and pain. The histology highlighted the presence of intraepithelial cell ballooning, confirming the diagnosis of HSV-1 infection.
单纯疱疹病毒1型（HSV-1）是一种非常常见的感染，通常局限于唇部的黏膜皮肤交界处。很少情况下，在牙周组织中也能检测到，这与牙周疾病进展和牙龈退缩风险升高有关。最近，文献报道HSV-1与多种合并感染与冠状病毒及随后的COVID-19疾病有关。本报告阐述了1例COVID-19感染患者的HSV-1病例，该患者上颌牙齿牙龈边缘出现溃疡和水疱，并伴有酸痛。组织学检查突出显示上皮内细胞气球样变，证实为HSV-1感染。
