Contreras A, Slots J
Department of Periodontology, School of Dentistry, University of Southern California, Los Angeles 90089-0641, USA.
Oral Microbiol Immunol. 2001 Feb;16(1):63-4. doi: 10.1034/j.1399-302x.2001.160111.x.
Herpes simplex virus (HSV) is frequently detected in gingival crevicular fluid and in gingival biopsies of periodontal lesions; however, the relative occurrence of HSV type 1 and 2 in periodontal specimens has not been established. This investigation used type-specific polymerase chain reaction (PCR) to detect the presence of HSV-1 and HSV-2 in periodontal pocket samples from 26 patients who had previously been revealed to have periodontal HSV by PCR amplification of a gene shared by HSV-1 and HSV-2. HSV-1 was detected in all 26 periodontal pocket specimens and HSV-2 was not detected. Apparently, HSV-2 is a rare inhabitant of periodontal sites.
单纯疱疹病毒（HSV）在龈沟液和牙周病变的牙龈活检组织中经常被检测到；然而，HSV-1和HSV-2在牙周标本中的相对发生率尚未确定。本研究采用型特异性聚合酶链反应（PCR），对26例先前通过HSV-1和HSV-2共享基因的PCR扩增显示患有牙周HSV的患者的牙周袋样本进行检测，以确定HSV-1和HSV-2的存在情况。在所有26个牙周袋标本中均检测到HSV-1，未检测到HSV-2。显然，HSV-2是牙周部位的罕见寄居者。
