Radiology Department, China-Japan Union Hospital of Jilin University.
Cardiology Department, China-Japan Union Hospital of Jilin University;
J Vis Exp. 2022 Jul 20(185). doi: 10.3791/63598.
Atrial fibrillation (AF) is the most common form of arrhythmia. Atrial remodeling is considered the most critical mechanism for the presence and development of atrial fibrillation. Also, atrial remodeling can lead to the enlargement and dysfunction of the left atrium (LA), resulting in thrombosis and heart failure. Functional changes in left atrial strain and strain rate occur before structural alterations and are closely associated with structural remodeling and left atrial fibrosis. These parameters are sensitive biomarkers for atrial function. Cardiac magnetic resonance feature tracking (CMR-FT) is a novel, non-invasive, post-processing technique that can evaluate left atrial strain and strain rate. The CMR-FT was utilized in this investigation to assess the bilateral atrium strain rate in individuals with paroxysmal AF. Modifications in each segmental strain were evaluated using segmental analysis. The CMR-FT is recommended for non-invasive evaluations in the clinical assessment of atrial strain among existing strain imaging techniques. Further, it is a flexible parameter measurement with good reproducibility, high soft-tissue resolution, and post-processing based on standard cine balanced steady-state free precision (bSSFP) long-axis images without requiring a new sequence acquisition.
心房颤动（AF）是最常见的心律失常形式。心房重构被认为是心房颤动发生和发展的最关键机制。此外，心房重构可导致左心房（LA）扩大和功能障碍，从而导致血栓形成和心力衰竭。左心房应变和应变速率的功能变化先于结构改变，与结构重构和左心房纤维化密切相关。这些参数是心房功能的敏感生物标志物。心脏磁共振特征追踪（CMR-FT）是一种新颖的、非侵入性的后处理技术，可评估左心房应变和应变速率。本研究利用 CMR-FT 评估阵发性 AF 患者双侧心房的应变率。通过节段分析评估每个节段应变的变化。CMR-FT 被推荐用于现有应变成像技术中，对心房应变进行临床评估的非侵入性评估。此外，它是一种灵活的参数测量，具有良好的可重复性、高软组织分辨率和基于标准电影平衡稳态自由进动（bSSFP）长轴图像的后处理，无需新的序列采集。
